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首页> 外文期刊>Endoscopy: Journal for Clinical Use Biopsy and Technique >Guidelines of the European Society of Gastrointestinal Endoscopy (E.S.G.E.) antibiotic prophylaxis for gastrointestinal endoscopy. European Society of Gastrointestinal Endoscopy.
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Guidelines of the European Society of Gastrointestinal Endoscopy (E.S.G.E.) antibiotic prophylaxis for gastrointestinal endoscopy. European Society of Gastrointestinal Endoscopy.

机译：欧洲胃肠内窥镜学会（E.S.G.E.）胃肠道内窥镜抗生素预防指南。欧洲胃肠内窥镜学会。

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There are two situations when antibiotic prophylaxis is recommended. The first is associated with procedures known to be followed by high rates of bacteraemia, involving organisms prone to cause endocarditis. These include oesophageal dilatation, variceal sclerotherapy and laser therapy in the upper gastrointestinal tract. As bacteraemia following these procedures is usually harmless in average risk patients antibiotic prophylaxis is recommended only for a patient with a lesion susceptible to endocarditis or one who is at increased risk of symptomatic bacteraemia due to neutropenia or immunosuppression. In most cases parenteral amoxycillin and gentamicin is recommended plus metronidazole for neutropenic patients. Vancomycin or teicoplanin replace amoxycillin in a case of allergy. The second situation concerns procedures with a high incidence of local infection or which may lead to serious sepsis. These include therapeutic retrograde cholangiopancratography and percutaneous endoscopic gastrostomy where antibiotic prophylaxis is recommended even in average risk patients. Several antibiotics are recommended including oral ciprofloxacin or parenteral gentamicin or quinolone for ERCP and amoxycillin for PEG or cephalosporin or ureidopenicillin for both.
机译：建议在两种情况下进行抗生素预防。第一种与已知伴随高菌血症发生率的程序有关，涉及容易引起心内膜炎的生物体。这些包括食道扩张，静脉曲张硬化疗法和上消化道激光疗法。由于遵循这些程序进行的菌血症通常对一般风险患者无害，因此建议仅对患有心内膜炎的病变患者或因中性粒细胞减少或免疫抑制而导致症状性菌血症风险增加的患者进行抗生素预防。在大多数情况下，对于中性粒细胞减少的患者，建议肠胃外应用阿莫西林和庆大霉素加甲硝唑。万古霉素或替考拉宁在过敏的情况下代替阿莫西林。第二种情况涉及局部感染发生率高或可能导致严重败血症的手术。这些措施包括治疗性逆行胰胆管造影术和经皮内窥镜胃造口术，即使在中等风险的患者中也建议预防使用抗生素。建议使用几种抗生素，包括口服环丙沙星或肠胃外庆大霉素或喹诺酮类药物用于ERCP，阿莫西林用于PEG或头孢菌素或尿嘧啶青霉素。

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