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首页> 外文期刊>Irish Veterinary Journal >A survey of antibodies to pestivirus in sheep in the Republic of Ireland
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A survey of antibodies to pestivirus in sheep in the Republic of Ireland

机译：爱尔兰共和国绵羊瘟疫病毒抗体调查

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摘要

Sera from 1,448 adult ewes in 91 flocks, representing all 26 counties in the Republic of Ireland, were examined for pestivirus antibodies using a commercially available ELISA which detected IgG_1 antibody to border disease virus. Eighty-one sheep (5.6%) in 42 flocks (46.0%) were antibody-positive. Within infected flocks, the mean seroprevalence level was 11.4% with a range of 6.3% to 30.0%. The highest antibody prevalence was detected in sheep from central lowland counties of Ireland. Comparative neutralisation testing of 42 ELISA-positive sera detected geometric mean antibody titres of 136 to the NADL strain of bovine viral diarrhoea virus (BVDV), 92 to the Moredun strain of border disease virus and 21 to the 137/4 strain of border disease virus. These results suggest that BVDV may be the major ruminant pestivirus infecting sheep in Ireland. Although there are high numbers of infected flocks, many sheep within such flocks remain antibody-negative and are at risk of giving birth to lambs with congenital border disease.
机译：使用可检测到边界病病毒的IgG_1抗体的市售ELISA检查了代表爱尔兰共和国所有26个县的91个鸡群中1,448头成年母羊的血清中的瘟病毒抗体。 42个鸡群（46.0％）中的八十一只羊（5.6％）呈抗体阳性。在受感染的鸡群中，平均血清阳性率是11.4％，范围是6.3％至30.0％。在爱尔兰中部低地县的绵羊中检测到最高的抗体流行率。对42种ELISA阳性血清进行比较中和测试，检测到牛病毒性腹泻病毒（BVDV）的NADL株的几何平均抗体滴度为136，边界病病毒的Moredun株为92，边界病病毒的137/4株为21 。这些结果表明，BVDV可能是感染爱尔兰绵羊的主要反刍动物瘟病毒。尽管受感染的羊群数量很多，但这些羊群中的许多绵羊仍呈抗体阴性，并有可能生出患有先天性边境疾病的羔羊。

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