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首页> 外文期刊>Equine Veterinary Education >Osseous metaplasia in the conjunctiva of a horse presenting with recurrent ulcerative keratitis.
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Osseous metaplasia in the conjunctiva of a horse presenting with recurrent ulcerative keratitis.

机译：马结膜中的骨化生，表现为复发性溃疡性角膜炎。

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A 13-year-old Thoroughbred gelding presented with a 6 month history of recurrent conjunctivitis, dacryocystitis and corneal ulceration affecting the left eye (OS). Treatment had included multiple topical antibiotic and anti-inflammatory preparations, nasolacrimal system flushing and an injection of methylprednisolone acetate (MPA) (Depomedrone)1 administered subconjunctivally into the left lower eyelid. No mechanical cause for the ulcerative keratitis could be visualised but digital palpation revealed a firm linear structure in the central palpebral conjunctiva of the lower eyelid. An excisional biopsy was performed and histopathological examination revealed the lesion to be a region of osseous metaplasia. Following excision of the lesion, the corneal ulcer resolved and the eye remained disease free over a 4 year follow-up period. A causal link between the osseous metaplasia and the recurrent ulcerative keratitis was therefore suspected. This report describes the management of this case and discusses the pathogenesis of osseous metaplasia and the use of subconjunctival corticosteroids.Digital Object Identifier http://dx.doi.org/10.1111/j.2042-3292.2010.00214.x
机译：一位13岁的纯种马出现了6个月的复发性结膜炎，泪囊炎和影响左眼（OS）的角膜溃疡病史。治疗方法包括多种局部抗生素和抗炎制剂，鼻泪系统冲洗和结膜下左眼睑注射醋酸甲基强的松龙（MPA）（Depomedrone） 1 。看不到溃疡性角膜炎的机械原因，但触诊显示下睑中央睑结膜有牢固的线性结构。进行了切除活检，并且组织病理学检查显示病变是骨化生的区域。切除病灶后，角膜溃疡得以解决，并且在4年的随访期内，眼睛仍然没有疾病。因此怀疑骨化生与复发性溃疡性角膜炎之间存在因果关系。本报告介绍了该病例的处理方法，并讨论了骨化生的发病机制以及结膜下皮质类固醇的使用。Digital Object Identifier http://dx.doi.org/10.1111/j.2042-3292.2010.00214.x

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