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Clinical Commentary - Mimicry in neoplasia: When tumours don't play fair

机译：临床评论-瘤形成中的拟态：当肿瘤表现不正常时

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摘要

Followhg conception, normal development of the embryo in utero involves the differentiation and growth of the integument, skeleton, alimentary tract, muscles, gaments and tendons, heart and blood vessels, endocrine organs and other diverse organ systems. These structures are composed of tissues that derive from a population of multipotent stem cells with the capacity to from "he parenchymatous cells characteristic of the organ in question. The fertilised egg can be viewed as a totipotent stem cell, capable of forming all elements of the body. Neoplasia is cell proliferation out of control and there is renewed interest in the hypothesis that some forms of cancer are stem cell proliferative disorders (Trosko 2009). the stem cell hypothesis of cancer has many attractive features which includes an ability to account for mixed ours, such as those of the sweat glands or mammary gancls which might contain a mixture of secretory epithelial and contractile myoepithelial cells.
机译：遵循观念，子宫内胚胎的正常发育涉及外皮，骨骼，消化道，肌肉，结膜和肌腱，心脏和血管，内分泌器官和其他多种器官系统的分化和生长。这些结构由多能干细胞群组成的组织组成，这些组织具有“所讨论器官的特征性薄壁组织细胞的能力。受精卵可以看作是全能干细胞，能够形成所有的干细胞。”瘤形成是指细胞增殖失控，人们对某些形式的癌症是干细胞增殖性疾病的假说有了新的兴趣（Trosko 2009），癌症的干细胞假说具有许多吸引人的特征，其中包括能够解释混合性我们的，例如汗腺或乳腺，可能含有分泌性上皮细胞和收缩性肌上皮细胞的混合物。

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