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首页> 外文期刊>Equine and Comparative Exercise Physiology >Acute vascular occlusion in horses: effects on skeletal muscle size and blood flow.
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Acute vascular occlusion in horses: effects on skeletal muscle size and blood flow.

机译：马的急性血管阻塞：对骨骼肌大小和血流的影响。

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The purpose of this study was to demonstrate whether acute vascular occlusion was safe and if it would result in changes to limb muscle size in horses. Six healthy, unfit Standardbred mares were used. Horses (standing at rest) wore an occlusion cuff at the most proximal position of the left forelimb. The right forelimb was used as control. An occlusion pressure of 200 mmHg was set for 5 min followed by a 2 min recovery. Three sets of occlusions were given to each horse. Muscle thickness was measured using B-mode ultrasound. The circumference of the forelimb and first phalanx was measured using a flexible tape measure. Pulsed-wave Doppler was performed on the radialis artery with a 5-10 MHz mechanical transducer at baseline and at each occlusion. Peak flow velocity (PFV) and the flow velocity integral (FVI) were measured each time. Mid-forelimb, but not first phalanx, girth was increased (P<0.05) in the occluded but not in the control leg following occlusion. Extensor and flexor muscle thickness was increased (P<0.05) in the occluded but not in the control leg. There were no changes (P>0.05) in PFV or FVI at any measurement time point. Acute vascular occlusion may be a suitable and safe model for studying muscle hypertrophy in horses.
机译：这项研究的目的是证明急性血管闭塞是否安全，是否会导致马肢肌肉尺寸改变。使用了六只健康不健康的标准母马。马（站立时处于静止状态）在左前肢的最近端戴着封套。右前肢用作对照。设定200 mmHg的阻塞压力5分钟，然后恢复2分钟。给每匹马三组闭塞。使用B型超声测量肌肉厚度。使用柔性卷尺测量前肢和第一指骨的周长。在基线和每次阻塞时，使用5-10 MHz机械换能器对the动脉进行脉冲多普勒检查。每次测量峰值流速（PFV）和流速积分（FVI）。闭塞后，上肢中部，但不包括第一指骨，围长增加（P <0.05），而对照腿中未增加。被闭塞者的伸肌和屈肌厚度增加（P <0.05），而对照组则没有。在任何测量时间点，PFV或FVI均无变化（P> 0.05）。急性血管阻塞可能是研究马肌肉肥大的合适且安全的模型。

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