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Effect of Aspect Ratio on Chemical Reactions on Microchip

机译:长宽比对微芯片化学反应的影响

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Parallel two-phase laminar flow,which is formed when two solutions flow in microchannels,has been developed and has advanced unique research in the area of microchip analysis.In two-phase laminar flow,channel size has a significant effect on the efficiency of chemical reactions.However,the sizes of microchannels vary greatly in many studies.In this paper,we report on the effect of microchannel size on chemical reactions on a microchip.Aspect ratio is defined as the ratio of depth to width of a microchannel.Five microchips with different aspect ratios (from 0.50 to 2.00) were fabricated by mechanical machining.The reaction of nitrous acid and Saltzman reagent was carried out on these microchips and the absorbance was measured on-line in a capillary tube,which was attached to the outlet on the microchip.The results showed that the color reaction occurred more efficiently as the aspect ratio increased.This result is expected to be useful when determining the size of microchannels.
机译:平行两相层流是在微通道中两种溶液流动时形成的,并在微芯片分析领域具有独特的先进研究。在两相层流中,通道大小对化学效率有重要影响但是,在许多研究中,微通道的尺寸差异很大。在本文中,我们报道了微通道尺寸对微芯片化学反应的影响。纵横比定义为微通道的深度与宽度之比。五个微芯片通过机械加工制备不同纵横比(0.50至2.00)的样品。亚硝酸与Saltzman试剂在这些微芯片上进行反应,并在毛细管上在线测量吸光度,该毛细管连接至结果表明,随着长宽比的增加,显色反应会更有效地发生,这一结果有望在确定微通道尺寸时有用。

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