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首页> 外文期刊>Epilepsia: Journal of the International League against Epilepsy >Do nonspecific focal EEG slowing and epileptiform abnormalities favor one hemisphere?
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Do nonspecific focal EEG slowing and epileptiform abnormalities favor one hemisphere?

机译：非特异性局灶性脑电图减慢和癫痫样异常是否有利于一个半球？

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PURPOSE: Several EEG-based studies suggest that epileptiform activity originates from the left more than the right hemisphere. In contrast, other pathophysiologies such as stroke lateralize relatively symmetrically. Study of focal slowing and other EEG abnormalities allows assessment of favoring as well as referral and interpretation bias. METHODS: The 1,331 consecutive adult EEG reports were reviewed for epileptiform discharges (EDs) and nonepileptiform focal slowing. Side of slowing or EDs, interpreting electoencephalographer, and whether the patient was undergoing long-term monitoring or routine EEG were tallied. Results were statistically analyzed. RESULTS: Focal slowing occurred symmetrically; EDs favored the left hemisphere (p < 0.01). CONCLUSIONS: The left hemisphere may be more prone to epileptiform abnormalities in adults, but not to the nonspecific pathophysiologic processes that cause slowing. These findings suggest that potential interpretation bias does not influence left hemispheric favoring of EDs and instead may implicate a biologic etiology.
机译：目的：一些基于脑电图的研究表明，癫痫样活动起源于左侧而不是右侧半球。相反，其他病理生理学例如中风相对对称地横向化。对局灶性减慢和其他脑电图异常的研究可以评估偏爱以及转诊和解释偏见。方法：对1,331例成人脑电图连续报告进行了癫痫样放电（ED）和非脂肽样病灶减慢的回顾。对减慢或急诊的一面，解释为脑电图专家，以及患者是否正在接受长期监测或常规脑电图检查。对结果进行统计分析。结果：局灶性减慢对称发生。急诊部偏爱左半球（p <0.01）。结论：成人左半球可能更容易出现癫痫样畸形，但非特异性的病理生理过程却不会引起这种情况。这些发现表明，潜在的解释偏差不会影响左半球对ED的偏爱，而可能暗示了生物学病因。

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