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首页> 外文期刊>Epilepsia: Journal of the International League against Epilepsy >Risk of recurrence after a first unprovoked seizure.
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Risk of recurrence after a first unprovoked seizure.

机译:首次无故癫痫发作后复发的风险。

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摘要

The risk of recurrence after a first unprovoked seizure has been examined in numerous observational studies and two large, high-quality randomized trials. Overall, in untreated individuals, 40-50% can expect a recurrence within 2 years of the initial seizure. Treatment may reduce this risk by as much as half. Those at the greatest risk of recurrence have either an abnormal EEG or an identifiable neurological condition or symptoms consistent with one ("symptomatic"). Status epilepticus and a history of febrile seizures may be associated with an increased risk of recurrence in individuals with symptomatic seizures. The great majority of people (approximately 90%) who are seen for a first unprovoked seizure attain a one to two year remission within 4 or 5 years of the initial event.
机译:在众多观察性研究和两项大型,高质量的随机试验中,已经检查了首次无故癫痫发作后复发的风险。总体而言,未经治疗的个体中,有40%至50%的患者可以在最初发作后的2年内复发。治疗可以将这种风险降低多达一半。那些复发风险最大的人可能患有异常的脑电图或可识别的神经系统疾病或与一种症状一致的症状(“有症状的”)。癫痫持续状态和高热惊厥史可能与有症状的惊厥患者复发的风险增加有关。初次无故癫痫发作的绝大多数人(约90%)在初次事件发生后的4到5年内可缓解1到2年。

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