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首页> 外文期刊>Epilepsia: Journal of the International League against Epilepsy >High frequency oscillations (80-500 Hz) in the preictal period in patients with focal seizures
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High frequency oscillations (80-500 Hz) in the preictal period in patients with focal seizures

机译:局灶性癫痫发作前期的高频振荡(80-500 Hz)

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Summary:Purpose:Intracranial depth macroelectrode recordings from patients with focal seizures demonstrate interictal and ictal high frequency oscillations (HFOs, 80-500 Hz). These HFOs are more frequent in the seizure-onset zone (SOZ) and reported to be linked to seizure genesis. We evaluated whether HFO activity changes in a systematic way during the preictal period.Methods: Fifteen minutes of preictal intracranial electroencephalography (EEG) recordings were evaluated in seven consecutive patients with well-defined SOZ. EEG was filtered at 500 Hz and sampled at 2,000 Hz. Ripples (80-250 Hz) and fast ripples (250-500 Hz) were visually marked, and spectral analysis was performed in seizure-onset as well as nonseizure-onset channels.
机译:摘要:目的:局灶性癫痫患者的颅内深度宏电极记录显示发作和发作的高频振荡(HFO,80-500 Hz)。这些HFO在癫痫发作区(SOZ)更为频繁,并据报道与癫痫发作的发生有关。我们评估了HFO活性在发作前是否以系统的方式改变。方法:对连续7例SOZ明确的患者进行了15分钟的发作前颅内脑电图(EEG)记录。脑电图以500 Hz过滤并以2,000 Hz采样。在视觉上标记出波纹(80-250 Hz)和快速波纹(250-500 Hz),并在发作发作和非发作发作的通道中进行了频谱分析。

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