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Two populations are better than one.

机译:两个人口比一个人口好。

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摘要

Given that febrile seizures (FSs) are the most common seizure "syndrome" of childhood occurring in 2 to 4 percent of individuals, one would think that clear definitions and descriptors based upon data are available. However, when one digs not very far below the surface, one finds some fundamental gaps. In 1980, the National Institutes of Health (1) convened a consensus conference to approach a number of critical questions such as, "What is a febrile seizure?"as well as attendant risks (injury, repeat febrile and afebrile seizures, benefits and risks of prophylaxis and management). The consensus suggested that these seizures usually occurred between 3 months and 5 years, but otherwise did not provide guidance as to how long the seizures last or any basis for distinguishing those that were prolonged from those that were not. However, a prolonged seizure was identified as one of the important risk factors predisposing the child to afebrile seizures. One of the seminal studies upon which this recommendation was based (and which we have used to counsel our families) defined prolonged as greater than 15 minutes and reported that this will occur in almost 8 percent of children with FS (2). The use of 10 to 15 minutes as the cut-point to identify seizures as prolonged has been adopted by subsequent reports (3-6).
机译:鉴于高热惊厥(FSs)是儿童中最常见的癫痫发作“综合征”,发生在2%到4%的个体中,因此人们会认为基于数据的明确定义和描述符是可用的。但是,当人们在地下不远处挖掘时,就会发现一些基本的差距。 1980年,美国国立卫生研究院(1)召开了一次共识会议,讨论了一些关键问题,例如“什么是高热惊厥?”以及随之而来的风险(伤害,反复高热和低热惊厥,益处和风险)。预防和管理)。共识表明,这些癫痫发作通常发生在3个月至5年之间,但没有提供有关癫痫发作持续多长时间的指导,也没有提供任何依据来区分长期发作和非长期发作。然而,长时间的癫痫发作被确定为使儿童容易出现高热性癫痫发作的重要危险因素之一。这项建议所基于的一项开创性研究(我们曾用来为家人提供咨询)将延长时间定为超过15分钟,并报告说这种情况将在几乎8%的FS儿童中发生(2)。随后的报告(3-6)已经采用了10到15分钟作为确定癫痫发作时间的切入点。

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