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首页> 外文期刊>Brachytherapy >The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma
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The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma

机译：葡萄膜黑色素瘤和视网膜母细胞瘤的斑块近距离治疗的美国近距离治疗学会共识指南

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Purpose: To present the American Brachytherapy Society (ABS) guidelines for plaque brachytherapy of choroidal melanoma and retinoblastoma. Methods and Materials: An international multicenter Ophthalmic Oncology Task Force (OOTF) was assembled to include 47 radiation oncologists, medical physicists, and ophthalmic oncologists from 10 countries. The ABS-OOTF produced collaborative guidelines, based on their eye cancer-specific clinical experience and knowledge of the literature. This work was reviewed and approved by the ABS Board of Directors as well as within the journal's peer-reivew process. Results: The ABS-OOTF reached consensus that ophthalmic plaque radiation therapy is best performed in subspecialty brachytherapy centers. Quality assurance, methods of plaque construction, and dosimetry should be consistent with the 2012 joint guidelines of the American Association of Physicists in Medicine and ABS. Implantation of plaque sources should be performed by subspecialty-trained surgeons. Although there exist select restrictions related to tumor size and location, the ABS-OOTF agreed that most melanomas of the iris, ciliary body, and choroid could be treated with plaque brachytherapy. The ABS-OOTF reached consensus that tumors with gross orbital extension and blind painful eyes and those with no light perception vision are unsuitable for brachytherapy. In contrast, only select retinoblastomas are eligible for plaque brachytherapy. Prescription doses, dose rates, treatment durations, and clinical methods are described. Conclusions: Plaque brachytherapy is an effective eye and vision-sparing method to treat patients with intraocular tumors. Practitioners are encouraged to use ABS-OOTF guidelines to enhance their practice.
机译：目的：介绍脉络膜黑色素瘤和视网膜母细胞瘤斑块近距离放射治疗的美国近距离放射治疗学会（ABS）指南。方法和材料：组成了一个国际多中心眼科肿瘤特别工作组（OOTF），其中包括来自10个国家的47位放射肿瘤学家，医学物理学家和眼科肿瘤专家。 ABS-OOTF根据他们特定于眼癌的临床经验和文献知识，制定了合作指南。该工作已由ABS董事会以及该期刊的同行评审过程进行了审查和批准。结果：ABS-OOTF达成共识，即在专业近距离放射治疗中心最好进行眼斑放射治疗。质量保证，噬菌斑构建方法和剂量测定应与2012年美国医学物理学会和ABS联合指南相一致。斑块源的植入应由经过专业培训的外科医生进行。尽管存在与肿瘤大小和位置有关的选择性限制，但ABS-OOTF同意，可以通过斑块近距离放射治疗来治疗大多数虹膜，睫状体和脉络膜黑色素瘤。 ABS-OOTF达成共识，即眼眶扩张，眼睛盲目疼痛，无视力视觉的肿瘤不适合近距离放射治疗。相反，只有部分视网膜母细胞瘤才有资格进行斑块近距离放射治疗。描述了处方剂量，剂量率，治疗持续时间和临床方法。结论：斑块近距离放射疗法是治疗眼内肿瘤患者的一种有效的保留视力的方法。鼓励从业人员使用ABS-OOTF准则来加强实践。

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