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Short-term postoperative superiority and 5-year follow-up outcomes of video-assisted thoracoscopic esophagectomy for treatment of esophageal carcinoma: a historical comparison with conventional open esophagectomy under a single experienced surgeon

机译:电视胸腔镜食管切除术治疗食管癌的短期术后优越性和5年随访结果:在一名经验丰富的外科医师的支持下与常规开放式食管切除术的历史比较

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Background Few reports have provided a direct comparison of thoracoscopic and open esophagectomy for treatment of esophageal carcinoma in a sufficiently large number of patients with an adequate follow-up period. Methods We compared the short- and long-term (up to 5 years after surgery) outcomes of 121 patients who had undergone video-assisted thoracoscopic esophagectomy with 3-field lymphadenectomy (the VATE group) and 74 patients who had undergone conventional open esophagectomy with 3-field lymphadenectomy (the OE group) for treatment of esophageal squamous cell carcinoma. Results Total and intrathoracic operation times were longer and total and intrathoracic blood losses were lower in the VATE group than in the OE group. The number of dissected lymph nodes around the left recurrent laryngeal nerve was significantly higher, while both the intensive care unit stay and postoperative hospital stay were significantly shorter in the VATE group. Moreover, the frequency of postoperative analgesia use was lower in the VATE group. Overall morbidity and mortality rates weresimilar, and the incidences of overall, surgical-site, and thoracic wound infections were significantly lower in the VATE group. Additionally, the incidence of postoperative pneumonia was also lower in the VATE group, although the difference was not statistically significant. No differences were observed in recurrence or survival rates. Conclusion Video-assisted thoracoscopic esophagectomy with 3-field lymphadenectomy is a safe and effective surgical method that can be used as an alternative to conventional open esophagectomy in patients with curable esophageal carcinoma.
机译:背景技术很少有报道直接比较胸腔镜和开放式食管切除术在足够多的随访期间对足够多的患者进行食道癌的治疗。方法我们比较了121例行电视辅助胸腔镜食管切除术加三视野淋巴结清扫术(VATE组)和74例行常规开放性食管切除术的患者的短期和长期(术后5年)结局。 3场淋巴结清扫术(OE组)用于治疗食道鳞状细胞癌。结果VATE组的总手术时间和胸腔内手术时间都比OE组更长,总的和胸腔内失血量更低。 VATE组左喉返神经周围解剖的淋巴结数目明显增多,而重症监护病房住院时间和术后住院时间均明显缩短。此外,VATE组术后镇痛的频率较低。 VATE组的总体发病率和死亡率相似,并且总体,手术部位和胸腔伤口感染的发生率均显着降低。此外,VATE组术后肺炎的发生率也较低,尽管差异无统计学意义。在复发率或生存率方面均未观察到差异。结论电视胸腔镜食管切除术联合三视野淋巴结清扫术是一种安全有效的手术方法,可替代传统的开放式食管癌根治术。

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