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首页> 外文期刊>Esophagus >Predictive factors for postoperative tachyarrhythmia after thoracoscopic esophagectomy and the usefulness of landiolol hydrochloride for its treatment
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Predictive factors for postoperative tachyarrhythmia after thoracoscopic esophagectomy and the usefulness of landiolol hydrochloride for its treatment

机译：胸腔镜食管切除术后术后快速性心律失常的预测因素及盐酸兰多洛尔的治疗作用

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Background Tachyarrhythmia after esophagectomy is a severe complication that should not be underestimated because of its negative impact. The aims of this study were to clarify the cause and impact of postoperative tachyarrhythmia after thoracoscopic esophagectomy. Additionally, we analyzed the usefulness of landiolol administration for postoperative tachyarrhythmia. Methods We evaluated the predictive factors for tachyarrhythmia onset after surgery and its clinical impact in 127 patients who underwent thoracoscopic esophagectomy with extended lymphadenectomy. Moreover, we analyzed the efficacy of landiolol for postoperative tachyarrhythmia. Results Tachyarrhythmia developed in 38 of the 127 patients. Multivariate analysis showed that advanced age, heart disease, and hyperlipidemia were associated with postoperative tachyarrhythmia. Hyponatremia, hypoalbumine-mia, and leukocytosis on postoperative day 3 were significantly associated with tachyarrhythmia onset. The incidence of all complications and respiratory complications, including pneumonia, was significantly higher in patients with than in those without tachyarrhythmia. The mortality rate in the tachyarrhythmia group tended to be higher than that in the nontachyarrhythmia group. Landiolol as a treatment for tachyarrhythmia immediately decreased heart rate and safely reduced subsequent respiratory complications. Conclusion In elderly patients with cardiac disease or hyperlipidemia, surgeons should be alert for the occurrence of tachyarrhythmia after esophagectomy. Postoperative tachyarrhythmia is a marker of morbidities with particular emphasis on respiratory complications. However, it can be adequately managed by landiolol, resulting in fewer respiratory complications. Landiolol might be a safe and convenient agent for managing postoperative tachyarrhythmia after thoracoscopic esophagectomy, resulting in lower mortality and morbidity rates.
机译：背景食管切除术后的快速性心律失常是一种严重的并发症，由于其负面影响，因此不应低估。这项研究的目的是阐明胸腔镜食管切除术后术后快速性心律失常的原因和影响。此外，我们分析了使用兰地洛尔治疗术后快速性心律失常的有效性。方法我们评估了127例行胸腔镜食管切除术加扩展淋巴结清扫术的患者术后快速性心律失常的预测因素及其临床影响。此外，我们分析了兰地洛尔对术后快速性心律失常的疗效。结果127例患者中有38例发生了快速性心律失常。多因素分析表明，高龄，心脏病和高脂血症与术后快速性心律失常有关。术后第3天的低钠血症，低白蛋白血症和白细胞增多与快速性心律失常的发生密切相关。有合并快速性心律失常的患者的所有并发症和包括肺炎在内的呼吸系统并发症的发生率均明显高于无快速性心律失常的患者。快速性心律失常组的死亡率倾向于高于非快速性心律失常组的死亡率。兰地洛尔作为快速性心律失常的治疗方法，可立即降低心率并安全地减少随后的呼吸系统并发症。结论老年心脏病或高脂血症患者应警惕食管切除术后发生快速性心律失常。术后快速性心律失常是发病的标志，尤其着重于呼吸系统并发症。但是，羊毛脂可以适当地控制它，从而减少呼吸系统并发症。兰地洛尔可能是治疗胸腔镜食管切除术后的快速性心律失常的一种安全，便捷的药物，可降低死亡率和发病率。

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