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Endotracheal metastasis from basaloid squamous carcinoma of the esophagus

机译:食道基底样鳞状细胞癌的气管内转移

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摘要

Endobronchial metastases from extrapulmonary neoplasms are rare events, and there is no report in the literature of metastasis originating from esophageal cancer. Basaloid squamous carcinoma of the esophagus is a rare histologic type that is known to be a biologically aggressive phenotype. We describe a rare case of metachro-nous endotracheal metastasis originating from esophageal basaloid squamous carcinoma. A 72-year-old Japanese man underwent esophagectomy for stage I esophageal cancer. Pathological diagnosis of the resected specimen was basaloid squamous carcinoma. One year later, a follow-up computed tomography scan displayed a tumor shadow in the tracheal wall. Bronchoscopy revealed a protruding tumor in the tracheal wall, and the pathologic diagnosis of the biopsy specimen was also basaloid squamous carcinoma. According to the diagnosis of metachronous endobronchial metastasis from esophageal basaloid squamous carcinoma, we treated the patient with chemotherapy comprising docetaxel, cisplatin, and 5-fluorouracil followed by chemoradiotherapy, and complete response was achieved. The patient has not suffered a recurrence of the disease for 23 months since the diagnosis of the endobronchial tumor. Careful follow-up is needed to ensure that rare types of metastasis are not missed in cases with biologically aggressive tumors.
机译:来自肺外肿瘤的支气管内转移是罕见的事件,并且从食管癌转移的文献中也没有报道。食道鳞状鳞状上皮癌是一种罕见的组织学类型,已知具有生物学侵袭性表型。我们描述了一种罕见的起源于食管基底基底鳞状癌的气管内气管转移的病例。一名72岁的日本男子因I期食管癌接受了食管切除术。切除标本的病理诊断为基底样鳞状癌。一年后,后续的计算机断层扫描显示气管壁上有一个肿瘤阴影。支气管镜检查发现气管壁有突出的肿瘤,活检标本的病理诊断也为基底样鳞状癌。根据对食管基底基底鳞状细胞癌的异时支气管内转移的诊断,我们用多西他赛,顺铂和5-氟尿嘧啶化疗并随后放化疗对患者进行了治疗,并获得了完全缓解。自诊断出支气管内肿瘤以来,该患者已有23个月未复发。需要进行认真的随访,以确保在具有生物学侵袭性肿瘤的情况下不会遗漏稀有类型的转移。

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