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A case of lymph node metastasis after endoscopic mucosal resection of esophageal cancer invading the muscularis mucosa

机译:内镜黏膜切除食管癌侵犯肌层黏膜后淋巴结转移1例

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摘要

A 70-year-old man was diagnosed with a thoracic esophageal squamous cell carcinoma invading the muscularis mucosa without lymph node or distant metas-tases in June 2003. Endoscopic mucosal resection was conducted. Histological examination showed squamous cell carcinoma invading the deep mucosal layer without lymphatic permeation. In April 2006, a chest CT scan revealed a metastasis to the right recurrent laryngeal nerve chain (106recR) lymph node, and chemoradiotherapy and chemotherapies were performed but were not very effective. He died of esophagobronchial fistula in October 2007. We reexamined this case in detail, and a deeper cut of the block revealed positive lymph vessel invasion and droplet infiltrations. We were initially unable to identify lymphatic permeation but specific findings were determined, such as high degrees of cellular atypia, downward extension of irregular epithelial processes, and irregular margins of cancer alveoli. Extreme caution is required for treating patients with these morphological changes.
机译:2003年6月,一名70岁男子被诊断患有胸膜食管鳞状细胞癌,侵袭了肌层粘膜,无淋巴结转移或远处转移。进行了内镜下粘膜切除术。组织学检查显示鳞状细胞癌浸润深层粘膜层,无淋巴渗透。 2006年4月,胸部CT扫描显示右喉返神经链(106recR)淋巴结转移,进行了放化疗和化学疗法,但效果不佳。他于2007年10月死于食管支气管瘘。我们对该病例进行了详细的重新检查,对该块进行了更深的切割,显示出阳性的淋巴管浸润和液滴浸润。我们最初无法确定淋巴的渗透性,但是确定了一些具体的发现,例如高度的细胞异型性,不规则上皮过程的向下延伸以及癌泡的不规则边缘。治疗具有这些形态变化的患者时需要格外小心。

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