Ubiquitin: a potential cerebrospinal fluid progression marker in Huntington's disease

Vinther-Jensen T.; Simonsen A. H.; Budtz-Jorgensen E.; Hjermind L. E.; Nielsen J. E.

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Ubiquitin: a potential cerebrospinal fluid progression marker in Huntington's disease

机译：泛素：亨廷顿舞蹈病的潜在脑脊液进展标志

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Background: Finding early and dynamic biomarkers in Huntington's disease is a key to understanding the early pathology of Huntington's disease and potentially to tracking disease progression. This would benefit the future evaluation of potential neuroprotective and disease-modifying therapies, as well as aid in identifying an optimal time point for initiating a potential therapeutic intervention.

机译：背景：在亨廷顿氏病中发现早期和动态的生物标记物是了解亨廷顿氏病早期病理并潜在追踪疾病进展的关键。这将有利于将来对潜在的神经保护和疾病缓解疗法的评估，并有助于确定启动潜在治疗干预的最佳时间点。

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《European journal of neurology: the official journal of the European Federation of Neurological Societies》 |2015年第10期|共7页
作者
Vinther-Jensen T.; Simonsen A. H.; Budtz-Jorgensen E.; Hjermind L. E.; Nielsen J. E.;
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正文语种 eng
中图分类神经病学;
关键词
biomarkers; cerebrospinal fluid; Huntington's disease; premanifest; SELDI-TOF; ubiquitin;

机译：生物标志物;脑脊液;亨廷顿舞蹈病;预示;SELDI-TOF;泛素;

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1. Ubiquitin: a potential cerebrospinal fluid progression marker in Huntington's disease [J] . Vinther-Jensen T., Simonsen A. H., Budtz-Jorgensen E., European journal of neurology: the official journal of the European Federation of Neurological Societies . 2015,第10期

机译：泛素：亨廷顿舞蹈病的潜在脑脊液进展标志
2. Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease [J] . Filipe B. Rodrigues Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2021,第2期

机译：脑脊液和血液中的肠尿素途径代谢产物作为亨廷顿疾病的潜在生物标志物
3. Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer’s disease [J] . Umesh Gangishetti, J. Christina Howell, Richard J. Perrin, Alzheimer s Research & Therapy . 2018,第1期

机译：非β淀粉样蛋白/ tau脑脊髓液标记物可指导阿尔茨海默氏病的分期和进展
4. Identification and quantification of N-linked glycoproteins in human cerebrospinal fluid unique to Parkinson's disease or its progression [C] . Hyejin Hwang, Catherine Pan, Kathy Chung, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：对帕金森病的人脑脊液中N-连接糖蛋白的鉴定和定量帕金森病或进展
5. Development and quality control of diagnostic markers in cerebrospinal fluid and tissue samples in Creutzfeldt -Jakob disease [D] . Van Everbroeck, Bart R. J. 2001

机译：Creutzfeldt -Jakob病脑脊液和组织样本中诊断标志物的开发和质量控制
6. N-Terminally Truncated and Pyroglutamate-Modified Aβ Forms Are Measurable in Human Cerebrospinal Fluid and Are Potential Markers of Disease Progression in Alzheimer’s Disease [O] . Guido Domingo, Luisa Benussi, Claudia Saraceno, 2021

机译：N-末端截短的和吡酰磺酸酯改性的Aβ形式可在人脑脊液中测量并且是阿尔茨海默病的疾病进展的潜在标志物
7. High resolution discovery proteomics reveals candidate disease progression markers of Alzheimer's disease in human cerebrospinal fluid [O] . Hendrickson, RC, Lee, AY, Song, Q, 2015

机译：高分辨率发现蛋白质组学揭示人脑脊液中阿尔茨海默氏病的候选疾病进展标志物

Ubiquitin: a potential cerebrospinal fluid progression marker in Huntington's disease

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