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首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >Combined brain voxel-based morphometry and diffusion tensor imaging study in idiopathic Restless Legs Syndrome patients
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Combined brain voxel-based morphometry and diffusion tensor imaging study in idiopathic Restless Legs Syndrome patients

机译:结合脑体素的形态计量学和弥散张量成像研究在特发性躁动腿综合征患者中的应用

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Background and purpose: The aim of this study was to evaluate the presence of abnormalities in the brain of patients with restless legs syndrome (RLS) using voxel-based morphometry and diffusion tensor imaging (DTI). Methods: Twenty patients and twenty controls were studied. Voxel-based morphometry analysis was performed using statistical parametric mapping (SPM8) and FSL-VBM software tools. For voxel-wise analysis of DTI, tract-based spatial statistics (TBSS) and SPM8 were used. Results: Applying an appropriate threshold of probability, no significant results were found either in comparison or in correlation analyses. Conclusions: Our data argue against clear structural or microstructural abnormalities in the brain of patients with idiopathic RLS, suggesting a prevalent role of functional or metabolic impairment.
机译:背景与目的:本研究的目的是使用基于体素的形态计量学和弥散张量成像(DTI)来评估躁动腿综合征(RLS)患者大脑中异常的存在。方法:研究20例患者和20例对照。使用统计参数映射(SPM8)和FSL-VBM软件工具进行基于体素的形态分析。对于DTI的体素分析,使用了基于道的空间统计(TBSS)和SPM8。结果:应用适当的概率阈值,在比较或相关分析中均未发现明显结果。结论:我们的数据反对特发性RLS患者大脑中明显的结构或微结构异常,表明功能性或代谢性损伤普遍存在。

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