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首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >Monthly variation of multiple sclerosis activity in the southern hemisphere: Analysis from 996 relapses in Brazil
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Monthly variation of multiple sclerosis activity in the southern hemisphere: Analysis from 996 relapses in Brazil

机译：南半球多发性硬化症活动的每月变化：巴西996次复发的分析

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摘要

Background and purpose: Seasonal variations of multiple sclerosis (MS) activity have been reported, however, most data come from studies in the northern hemisphere. Methods: We reviewed medical records of MS patients living in Campinas region, Brazil. The first symptoms' date was defined as the relapse month. Climatic information included UV radiation index, median temperature, rainfall, and humidity. Results: Two hundred and nine patients were included. The incidence of relapses was highest in January (11.2%) and December (10.4%) and lowest in November (5.7%) and October (7.0%) (P<0.015). The months with highest incidence of relapses (December-January) had higher UV radiation index and humidity rates (P=0.032 and 0.040, respectively). Conclusion: Most exacerbations were in the spring/summer transition, which also showed higher UV radiation index and humidity rate. Along with other environmental factors, seasonal fluctuation contributes to MS activity.
机译：背景和目的：据报道多发性硬化症（MS）活动的季节性变化，但是，大多数数据来自北半球的研究。方法：我们回顾了居住在巴西坎皮纳斯地区的MS患者的病历。最初症状的日期定义为复发月份。气候信息包括紫外线辐射指数，中值温度，降雨和湿度。结果：包括29例患者。复发的发生率在1月（11.2％）和12月（10.4％）最高，11月（5.7％）和10月（7.0％）最低（P <0.015）。复发率最高的月份（12月至1月）具有较高的紫外线辐射指数和湿度速率（分别为P = 0.032和0.040）。结论：大多数恶化是在春夏季过渡期，这也显示出较高的紫外线辐射指数和湿度。与其他环境因素一起，季节性波动也会导致MS活动。

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