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首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >Mobility and balance in Parkinson's disease: a population-based study.
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Mobility and balance in Parkinson's disease: a population-based study.

机译：帕金森氏病的流动性和平衡性：一项基于人群的研究。

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BACKGROUND AND PURPOSE: To assess the clinical correlates of mobility and balance, and to identify the risk factors for falls in Parkinson's disease (PD). METHODS: One-hundred and nineteen PD patients underwent clinical examination and tests for mobility and balance using the Timed Up & Go (TUG) test, walking speed, and the measurement of postural sway. RESULTS: The fallers (35% of the subjects) performed significantly worse in the TUG test than the non-fallers, and they also had a slower walking speed (P = 0.037 and P = 0.006, respectively). The total Unified Parkinson's Disease Rating Scale (UPDRS) score and age were positively associated with the TUG-test score. The severity of the disease and the use of walking aids correlated negatively with the walking speed, whereas the use of dopamine agonists was positively associated with the walking speed. The UPDRS total score [odds ratio (OR) 1.04, 95% confidence intervals (CI) 1.01-1.07] and increased postural sway (OR 1.25, 95% CI 1.02-1.54) were independent risk factors for falling in PD. CONCLUSION: Advanced age and severity of the disease are related to impaired mobility and balance in PD patients. The severity of the disease and increased postural sway seem to be the most important independent risk factors for falling in PD.
机译：背景与目的：评估运动和平衡的临床相关性，并确定帕金森氏病（PD）跌倒的危险因素。方法：一百一十九名PD患者接受了临床检查，并通过定时走步（TUG）测试，步行速度和姿势摇摆测量进行了运动和平衡测试。结果：在TUG测试中，跌倒者（占受试者的35％）比非跌倒者表现更差，步行速度也较慢（分别为P = 0.037和P = 0.006）。帕金森病综合评分量表（UPDRS）总得分和年龄与TUG测试得分呈正相关。疾病的严重程度和助行器的使用与步行速度呈负相关，而多巴胺激动剂的使用与步行速度呈正相关。 UPDRS总分[赔率（OR）1.04，95％置信区间（CI）1.01-1.07]和体位增加（OR 1.25，95％CI 1.02-1.54）是PD下降的独立危险因素。结论：疾病的高龄和严重程度与PD患者的活动能力减退和平衡有关。疾病的严重程度和姿势摇摆增加似乎是PD下降的最重要的独立危险因素。

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