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首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >Impact of a weight loss program on migraine in obese adolescents
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Impact of a weight loss program on migraine in obese adolescents

机译：减肥计划对肥胖青少年偏头痛的影响

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Background and purpose: Increased headache frequency and severity have been observed in obese populations, but the real impact of a weight loss treatment on headache has not been studied. We investigated this issue in a sample of obese adolescents. Methods: In all, 135 migraineurs, aged 14-18 years, with body mass index (BMI) ≥97th percentile, participating in a 12-month-long program, were studied before and after treatment. The program included dietary education, specific physical training, and behavioral treatment. Results: Decreases in weight (P < 0.01), BMI (P < 0.01), waist circumference (P < 0.01), headache frequency (P < 0.01) and intensity (P < 0.01), use of acute medications (P < 0.05), and disability (P < 0.05) were observed at the end of the first 6-month period and were maintained through the second 6 months. Both lower baseline BMI and excess change in BMI were significantly associated with better migraine outcomes 12 months after the intervention program. Conclusions: Significant improvements in both adiposity and headache data were observed in obese adolescents with migraine who participated in a 12-month-long interdisciplinary intervention program for weight loss. Initial body weight and amount of weight loss may be useful for clinicians to predict migraine outcomes.
机译：背景与目的：在肥胖人群中观察到头痛频率和严重性增加，但是尚未研究减肥治疗对头痛的真正影响。我们在肥胖青少年样本中调查了此​​问题。方法：在治疗前后，共研究了135名年龄在14-18岁之间，体重指数（BMI）≥97％的移民，参加了为期12个月的研究。该计划包括饮食教育，专门的体育锻炼和行为治疗。结果：体重减轻（P <0.01），BMI（P <0.01），腰围（P <0.01），头痛频率（P <0.01）和强度（P <0.01），使用急性药物（P <0.05）在第一个6个月结束时观察到了残疾（P <0.05），并且在第二个6个月中一直保持这种状态。基线BMI降低和BMI过度变化均与干预计划后12个月的偏头痛预后明显相关。结论：肥胖偏头痛青少年参加了一项为期12个月的减肥跨学科干预计划，肥胖和头痛数据均得到了显着改善。初始体重和减肥量可能对临床医生预测偏头痛的结局有用。

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