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首页> 外文期刊>Brachytherapy >A dosimetric comparison of MammoSite high-dose-rate brachytherapy and Xoft Axxent electronic brachytherapy.
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A dosimetric comparison of MammoSite high-dose-rate brachytherapy and Xoft Axxent electronic brachytherapy.

机译：MammoSite高剂量近距离放射疗法和Xoft Axxent电子近距离放射疗法的剂量学比较。

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PURPOSE: Over 20,000 patients have been treated with partial breast irradiation (PBI) using the MammoSite balloon brachytherapy applicator (IBB). Recently, a new form of balloon-based PBI, Xoft Axxent electronic brachytherapy (KVB), which uses a 50-kV x-ray source, has been introduced. This analysis was undertaken to dosimetrically compare the results of treatment using these two methods of PBI. METHODS AND MATERIALS: The study population consisted of 15 patients previously treated with IBB. The planning CT scans from these 15 patients were used to construct hypothetical treatment plans using the source characteristics of the KVB device. The plans were then compared using the dosimetric parameters discussed below. RESULTS: The mean %V(90) was 99.6% vs. 99.0% (p=nonsignificant [ns]), the mean %V(100) was 96.5% vs. 96.5%, the mean %V(150) was 41.8% vs. 59.4% (p<0.05), the mean %V(200) was 11.3% vs. 32.0% (p<0.05), and the mean %V(300) was 0.4% vs. 6.7% (p<0.05) for the IBB and KVB methods, respectively. The mean ipsilateral breast %V(50) was 19.8% vs. 13.0% (p<0.05), the mean ipsilateral lung %V(30) was 3.7% vs. 1.1% (p<0.05), and the mean heart %V(5) was 59.2% vs. 9.4% (p<0.05) for the IBB and KVB methods, respectively. CONCLUSIONS: The IBB and KVB methods of PBI offer comparable target volume coverage; however, the KVB method is associated with an increased volume of breast tissue in the high-dose regions and a decreased dose to the adjacent normal tissues.
机译：目的：已经使用MammoSite球囊近距离放射治疗器（IBB）对20,000多例患者进行了部分乳房照射（PBI）。最近，已经引入了一种新的基于气球的PBI形式，即Xoft Axxent电子近距离放射治疗（KVB），它使用50 kV X射线源。进行该分析以剂量比较使用这两种PBI方法的治疗结果。方法和材料：研究人群包括15名先前接受过IBB治疗的患者。利用这15位患者的CT计划扫描，使用KVB设备的放射源特征来构建假设的治疗计划。然后使用下面讨论的剂量参数对计划进行比较。结果：平均％V（90）为99.6％vs. 99.0％（p =无意义[ns]），平均％V（100）为96.5％对96.5％，平均％V（150）为41.8％ vs. 59.4％（p <0.05），平均％V（200）为11.3％vs. 32.0％（p <0.05），平均％V（300）为0.4％vs. 6.7％（p <0.05）分别用于IBB和KVB方法。同侧乳房的平均％V（50）为19.8％vs.13.0％（p <0.05），同侧肺的平均％V（30）为3.7％vs. 1.1％（p <0.05），平均心脏％V （5）的IBB和KVB方法分别为59.2％和9.4％（p <0.05）。结论：PBI的IBB和KVB方法提供了可比较的目标体积覆盖率;然而，KVB方法与高剂量区域的乳腺组织体积增加和邻近正常组织的剂量减少有关。

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