...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology >A novel microbead-based microfluidic device for rapid bacterial identification and antibiotic susceptibility testing
【24h】

A novel microbead-based microfluidic device for rapid bacterial identification and antibiotic susceptibility testing

机译：一种基于微珠的新型微流控装置，可快速鉴定细菌并进行抗生素敏感性测试

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Effective treatment of infectious diseases depends on the ability to rapidly identify the infecting bacteria and the use of sensitive antibiotics. The currently used identification assays usually take more than 72 h to perform and have a low sensitivity. Herein, we present a microbead-based microfluidic platform that is highly sensitive and rapid for bacterial detection and antibiotic sensitivity testing. The platform includes four units, one of which is used for bacterial identification and the other three are used for susceptibility testing. Our results showed that Escherichia coli O157 at a cell density range of 10(1)-10(5) CFU/mu L could be detected within 30 min. Additionally, the effects of three antibiotics on E. coli O157 were evaluated within 4-8 h. Overall, this integrated microbead-based microdevice provides a sensitive, rapid, reliable, and highly effective platform for the identification of bacteria, as well as antibiotic sensitivity testing.
机译：传染病的有效治疗取决于快速识别感染细菌的能力和敏感抗生素的使用。当前使用的鉴定分析通常需要72小时以上才能完成，并且灵敏度较低。在本文中，我们提出了一种基于微珠的微流控平台，该平台对细菌检测和抗生素敏感性测试具有高度的敏感性和快速性。该平台包括四个单元，其中一个用于细菌鉴定，另外三个用于药敏测试。我们的结果表明，可以在30分钟内检测到细胞密度范围为10（1）-10（5）CFU /μL的大肠杆菌O157。此外，在4-8小时内评估了三种抗生素对O157大肠杆菌的作用。总体而言，这种基于微珠的集成微设备为细菌鉴定以及抗生素敏感性测试提供了灵敏，快速，可靠且高效的平台。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号