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首页> 外文期刊>European journal of clinical nutrition >Total energy expenditure in the elderly.
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Total energy expenditure in the elderly.

机译:老年人的总能源消耗。

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摘要

Chronic diseases and disabilities increase with age, affecting more than 60% of those over 75 y, and limiting activities in about half of them. Therefore, total energy expenditure (TEE) and its components are assessed separately in health and disease. An analysis of 568 doubly labelled water measurements in 'healthy' subjects (184 measurements in subjects over 65 years) suggests that there is a decrease of 0.69 and 0.43 MJ/day/decade respectively in men (standard weight 75 kg) and women (standard weight 67 kg). Physical activity (PA) accounted for 46% of the decrease in TEE, basal metabolic rate (BMR) for 44% of the decrease and thermogenesis (T) for the remaining 10%. TEE was found to be 10.79+/-2.09 and 8.62+/-1.49 MJ/day in 150 men and 100 women aged over 60 y, respectively. Of the total variance in TEE, measured with doubly labelled water over a 2 week period, 69% was considered to be due to differences between individuals, and 31% to differences within individuals. The variance due to PA plus T was threefold greater than that due to BMR. Physiological factors were far more important than methodological factors in influencing measurements of TEE, BMR and PA+T. An analysis of 136 measurements of TEE (doubly labelled water and bicarbonate-urea methods) in free-living elderly patients suffering from a variety of diseases suggests a frequent decrease in TEE, which may occur despite an increase in BMR. This is largely due to a reduction is PA (eg up to approximately 50% reduction), but in some cases it is also due to a reduction in BMR (loss of body weight). More comprehensive information is required about TEE and its components, partly because of a probable selection bias in recruitment of subjects participating in specific tracer studies, and partly because of the variable effects of different diseases and factors that operate at different times in the course of the same disease.
机译:慢性疾病和残障随着年龄增长而增加,影响了75岁以上人群中的60%以上,并限制了其中一半的活动。因此,在健康和疾病方面分别评估了总能量消耗(TEE)及其组成部分。对“健康”受试者中568个双标签水测量值(65岁以上受试者中184个测量值)的分析表明,男性(标准体重75公斤)和女性(标准体重)分别减少了0.69和0.43 MJ /天/天。体重67公斤)。体力活动(PA)占TEE下降的46%,基础代谢率(BMR)占下降的44%,生热(T)占其余10%。 150名60岁以上的男性和100名女性的TEE被发现分别为10.79 +/- 2.09和8.62 +/- 1.49 MJ /天。在两周内用双标签水测量的TEE总差异中,有69%被认为是由于个体之间的差异,而31%被认为是由于个体之间的差异。 PA加T引起的方差比BMR引起的方差大三倍。在影响TEE,BMR和PA + T的测量中,生理因素远比方法因素重要。对患有各种疾病的自由活动老年患者的136次TEE(双标记水和碳酸氢盐-尿素方法)测量结果的分析表明,尽管BMR升高,TEE仍会频繁下降。这主要是由于降低了PA(例如最多降低了约50%),但在某些情况下,还归因于BMR的降低(体重减轻)。需要有关TEE及其组成部分的更全面的信息,部分是由于在招募参加特定示踪剂研究的受试者时可能存在选择偏倚,部分是由于不同疾病和因素在治疗过程中的不同时间产生的可变影响。相同的疾病。

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