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首页> 外文期刊>European journal of clinical nutrition >Eating disorders: a situation of malnutrition with peculiar changes in the immune system.
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Eating disorders: a situation of malnutrition with peculiar changes in the immune system.

机译:饮食失调:营养不良,免疫系统发生特殊变化的情况。

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摘要

Eating disorders, such as anorexia nervosa and bulimia nervosa, are significant public health concerns for a great deal of the population, and thus are even considered to be epidemics. These syndromes have a common aim: the pursuit of a desirable and extremely low weight, which is obviously very far from the ideal body weight. Therefore, these patients show abnormal food behavior, leading to a situation of malnutrition. Nutrients play an important role in the development and functionality of the immune system. Thus, the assessment of immunological parameters acquires great interest as a useful tool to evaluate the nutritional status of these patients. In addition, it is very well known that a depleted immune system as a consequence of malnutrition is linked to an increased susceptibility to infections. However, an extensive literature has pointed out that anorexic patients, even though severely malnourished, are relatively free from infectious diseases. As the immune system is altered by distorted food behaviors, such as in case of eating disorders, the awareness of the characteristics of other systems involved in these pathologies, and therefore altered, would be very helpful for the understanding of the mechanisms triggered in these syndromes. In fact, the interactions among the immune system and the remaining systems in eating disorders are beginning to be studied. Finally, the main goal is to limit the evolution of these illnesses through an early diagnosis and appropriate therapy to subsequently get a constant and definitive cure for the patients.
机译:饮食失调,例如神经性厌食症和神经性贪食症,是许多人群关注的重大公共卫生问题,因此甚至被认为是流行病。这些综合症的共同目标是:追求理想的极低体重,这显然与理想体重相去甚远。因此,这些患者表现出异常的饮食行为,从而导致营养不良。营养在免疫系统的发育和功能中起重要作用。因此,作为评估这些患者营养状况的有用工具,免疫学参数的评估引起了极大的兴趣。另外,众所周知,由于营养不良导致免疫系统衰竭与感染易感性增加有关。但是,大量文献指出,厌食症患者即使营养不良,也相对没有传染病。由于免疫系统会因饮食行为异常而发生变化(例如饮食失调),因此了解与这些疾病有关的其他系统的特征,因此发生变化,对于理解这些综合征触发的机制非常有帮助。 。实际上,饮食系统中免疫系统与其余系统之间的相互作用已开始被研究。最后,主要目标是通过早期诊断和适当的治疗方法来限制这些疾病的发展,从而为患者提供持续而确定的治疗方法。

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