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首页> 外文期刊>European journal of clinical nutrition >Comparability of skinfold thickness to DXA whole-body total fat in their associations with serum triglycerides in youths
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Comparability of skinfold thickness to DXA whole-body total fat in their associations with serum triglycerides in youths

机译：年轻人皮肤皱纹厚度与DXA全身总脂肪及其与血清甘油三酯的相关性

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Objective:To determine the comparability of triceps and subscapular skinfold thicknesses with dual X-ray absorptiometry (DXA) whole-body total fat (kg) in relation to serum triglyceride (TG) levels and increased risk of elevated TG levels, and identified optimum skinfold cutoffs for screening purposes in US adolescents.Subjects/Methods:Data from triceps and subscapular skinfold thickness, DXA whole-body total fat and serum TGs were obtained from 1505 US adolescents ages 12.00-17.99 years, who participated in two continuous National Health and Nutrition Examination Survey (NHANES) cycles 2001-2004. Study associations were examined with linear and logistic models, and ROC (receiver operating characteristic) analyses were used to derive skinfold cutoffs for identifying the risk of elevated TG levels.Results:Using area under the curves (AUCs) as metrics of prediction accuracy (with bootstrapped 95% CIs), no significant differences were found between skinfolds and DXA logistic models for predicting elevated TG levels. Similarly, skinfold and DXA models had comparable precision in predicting continuous serum TG from bootstrapped root mean squared errors for both sexes. Population-adjusted marginal mean estimates indicated that youths whose skinfolds are in the top quartile had TG levels within 83-108 mg/dl. Skinfold cutoffs for predicting elevated estimated TG using ROC analyses showed that cutoffs decreased with age and ranged from 13 to 30 mm for ages 12-17, in yearly intervals.Conclusion:Skinfold thicknesses were comparable to DXA whole-body total fat in predicting serum TG levels. These skinfold cutoffs could be used in practical settings as a first pass screener for identifying US adolescents at risk of elevated serum TGs.
机译：目的：确定三头肌和肩s下皮褶厚度与双X射线吸收法（DXA）全身总脂肪（kg）相对于血清甘油三酸酯（TG）水平和高TG水平升高风险的可比性，并确定最佳皮褶受试者/方法：来自三头肌和肩cap下皮褶厚度，DXA全身总脂肪和血清TG的数据来自于1505位12.00-17.99岁的美国青少年，他们连续参加了两次美国国家卫生与营养调查考试调查（NHANES）周期为2001-2004。使用线性和逻辑模型检查研究关联，并使用ROC（接收器工作特征）分析得出皮褶截断值，以识别TG水平升高的风险。结果：使用曲线下面积（AUC）作为预测准确性的指标（自举95％CI），皮褶和DXA逻辑模型之间预测TG水平升高之间没有显着差异。同样，皮褶和DXA模型在根据自举的两性均方根误差预测连续血清TG方面具有相当的精度。人口调整后的边际均值估计表明，皮褶位于最前四分位的年轻人的TG水平在83-108 mg / dl之内。使用ROC分析预测皮下脂肪的临界值升高的趋势表明，皮下脂肪的临界值随着年龄的增长而降低，在12至17岁之间的范围为13mm至30mm，并且每年一次。结论：皮下厚度在预测血清TG方面与DXA全身总脂肪相当水平。这些皮褶切除物可在实际环境中用作首过筛查剂，以鉴定有升高血清TGs风险的美国青少年。

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