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首页> 外文期刊>European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society >A fourth ventricular ganglioneurocytoma representing with cerebellar epilepsy: A case report and review of the literature.
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A fourth ventricular ganglioneurocytoma representing with cerebellar epilepsy: A case report and review of the literature.

机译：代表小脑癫痫的第四个室性神经节神经细胞瘤：一例病例报告并文献复习。

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摘要

Fourth ventricular low-grade tumoral or dysplastic neuronal lesions have been reported as an epileptic focus for recently described cerebellar epilepsy in the form of repetitive and stereotyped attacks of hemifascial spasm, eye blinking, fascial movements, head deviation and dysautonomic manifestations. The case of a 3-month old infant having fourth ventricular mass with similar symptoms such as paroxysmal facial movements, eye blinking, eyelid contractions and abnormal head posture is reported in this article. After a few days of her admission, her attacks displayed a new form with altered consciousness and left limb jerks which were unresponsive to medical therapy. Following the surgical excision of the lesion 10 months ago, attacks disappeared and she is still seizure free. Histopathological diagnosis was ganglioneurocytoma. The seizures (which may be intractable in cerebellar epilepsy) are thought to have arisen from subcortical structures such as cerebellum, brain stem nuclei or the lesion itself.In the case of intractable episodes, surgical excision may prevent further seizures and help patients have a normal cognitive and motor development.
机译：第四脑室低度肿瘤或发育异常的神经元病变已被报道为最近描述的小脑癫痫的癫痫病灶，其形式为半肌筋膜痉挛，眨眼，筋膜运动，头部偏斜和功能失调表现的反复发作和定型发作。本文报道了一个3个月大的婴儿，其第四脑室有类似症状，例如阵发性面部运动，眨眼，眼睑收缩和头部姿势异常。入院几天后，她的发作表现出一种新形式，意识改变，左肢抽搐，对药物治疗无反应。在10个月前通过外科手术切除病变后，发作消失了，她仍然没有癫痫发作。组织病理学诊断为神经节神经细胞瘤。癫痫发作（在小脑癫痫中可能是难治的）被认为是由皮层下结构引起的，例如小脑，脑干核或病变本身。如果发生顽固性发作，手术切除可能会阻止进一步的癫痫发作并帮助患者正常认知和运动发展。

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