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首页> 外文期刊>European journal of gastroenterology and hepatology >Palpable epigastric liver as a physical sign of cirrhosis: a prospective study.
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Palpable epigastric liver as a physical sign of cirrhosis: a prospective study.

机译：可触及的上腹肝是肝硬化的物理体征：一项前瞻性研究。

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OBJECTIVE: Large numbers of patients present with abnormal liver function tests, but only a minority have significant liver disease. Physical examination may help in identifying patients with significant liver disease and in selecting patients who may require liver biopsy. Over a number of years we noted that a palpable liver in the epigastrium was common in patients with cirrhosis. The aim of this study was to evaluate this clinical sign in a cohort of patients undergoing liver biopsy. METHODS: We prospectively studied 138 consecutive patients undergoing liver biopsy in a university teaching hospital. The main outcome measure was liver fibrosis measured using the standard METAVIR scoring system. RESULTS: Thirty-eight patients had no fibrosis on biopsy, 11 patients had grade 1, eight patients had grade 2, 14 patients had grade 3 and 42 patients had grade 4 (cirrhosis). Palpable epigastric liver had a sensitivity of 86% and a specificity of 67% for the diagnosis of cirrhosis in this cohort. CONCLUSION: We suggest that a palpable liver in the epigastrium is a useful physical sign of cirrhosis in clinical practice.
机译：目的：大量患者肝功能检查异常，但只有少数患者患有严重的肝病。体格检查可能有助于识别患有严重肝病的患者，并帮助选择可能需要进行肝活检的患者。多年来，我们注意到在肝硬化患者中上腹部明显可见肝脏。这项研究的目的是评估一群接受肝活检的患者的临床体征。方法：我们前瞻性研究了一家大学教学医院连续138例接受肝活检的患者。主要结局指标是使用标准METAVIR评分系统测得的肝纤维化。结果：38例活检无纤维化，11例为1级，8例为2级，14例为3级，42例为4级（肝硬化）。在该队列中，可触及的上腹肝对肝硬化的诊断灵敏度为86％，特异性为67％。结论：我们认为上腹部的可触及肝脏是临床实践中有用的肝硬化体征。

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