首页> 外文期刊>European journal of gynaecological oncology >Endometrial cancer: asymptomatic endometrial findings. Characteristics of postmenopausal endometrial cancer.
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Endometrial cancer: asymptomatic endometrial findings. Characteristics of postmenopausal endometrial cancer.

机译:子宫内膜癌:无症状的子宫内膜发现。绝经后子宫内膜癌的特征。

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Endometrial cancer affects patients at every age, however it occurs more frequently in menopause (> 50) and in postmenopause (> 70). The most frequent symptoms are bleeding and vaginal discharge. When hematometra or pyometra is present the patient may feel pain. In some cases endometrial adenocarcinoma is asymptomatic and the diagnosis is casually made during ultrasound examination or by histological examination of a uterus surgically removed for other indications. In these cases the most frequent findings are polyps and abnormally increased thickness of the endometrial mucosa. In postmenopause polyps and abnormal endometrial thickness are usually limited to a small area and surrounded by atrophic mucosa. Higher incidence rates of endometrial cancer were correlated with polyps and an increased number of serous type tumors were identified in the > 65-year age group. Endometrial carcinoma may be estrogen correlated or non-estrogen associated. Patients in postmenopause are often affected by non-estrogen correlated endometrial carcinoma. According to Kurman and other authors the first type of endometrial adenocarcinoma (estrogen correlated) is characterized by low-grade malignancy. On the contrary, non-estrogen correlated neoplasia is more aggressive. In our case series including 102 women aged > 70 years with endometrial carcinoma we found that survival was correlated with stage and grading - early stages were the most frequent and the grade increased with stage. In fact all the patients with relapses had grade 2 or 3 adenocarcinomas. Thirty-one patients > 70 years (30.69%) had a non-endometrioid type of cancer.
机译:子宫内膜癌在每个年龄段都会影响患者,但是在更年期(> 50)和绝经后(> 70)更容易发生。最常见的症状是出血和白带。当存在血球或脓液时,患者可能会感到疼痛。在某些情况下,子宫内膜腺癌是无症状的,诊断可以在超声检查过程中或通过对因其他适应症而手术切除的子宫进行组织学检查来进行。在这些情况下,最常见的发现是息肉和子宫内膜粘膜厚度异常增加。绝经后息肉和子宫内膜厚度异常通常局限于一小区域,并被萎缩性粘膜所包围。子宫内膜癌的较高发病率与息肉相关,并且在> 65岁年龄组中发现了浆液性肿瘤数量增加。子宫内膜癌可能与雌激素有关或与非雌激素有关。绝经后患者通常会受到非雌激素相关的子宫内膜癌的影响。根据Kurman和其他作者的观点,第一类子宫内膜腺癌(与雌激素有关)的特征是恶性程度低。相反,非雌激素相关的瘤形成更具侵略性。在我们的病例系列中,包括102名年龄> 70岁的子宫内膜癌女性,我们发现生存率与分期和分级相关-早期是最常见的,分级随着阶段的增加而增加。实际上,所有复发患者均患有2或3级腺癌。三十一名> 70岁的患者(30.69%)患有非子宫内膜样癌。

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