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首页> 外文期刊>European journal of gynaecological oncology >Fallopian tube cancer associated with paraneoplastic dermatomyositis -- asymptomatic multivisceral exacerbated dermatomyositis mimicking recurrent widespread malignant disease: case report.
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Fallopian tube cancer associated with paraneoplastic dermatomyositis -- asymptomatic multivisceral exacerbated dermatomyositis mimicking recurrent widespread malignant disease: case report.

机译：与副肿瘤性皮肌炎相关的输卵管癌-模仿复发性广泛恶性疾病的无症状多脏器加重型皮肌炎：病例报告。

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OBJECTIVE: To report an uncommon case of a recurrent episode of primarily paraneoplastic dermatomyositis which was completely disconnected from the initially triggering malignancy and manifested as a silent pure multivisceral exacerbation. CASE: A 70-year-old woman presented with a pure multivisceral episode of dermatomyositis without characteristic musculo-cutaneous symptoms one year after successful treatment of fallopian tube carcinoma with complete resolvement of a concomittant paraneoplastic dermatomyositis. The uncommon manifestation of recurrent dermatomyositis involving the lungs, spleen and liver, both adrenal glands and abdominal lymph nodes, mimicked a highly disseminated recurrence of the fallopian tube cancer. Physicians participating in the interdisciplinary tumor board were misled to opt for reinductive chemotherapy. Only histologic diagnosis obtained from multiple biopsies uncovered the inflammatory nature of the disease and spared the patient unneeded chemotherapy. CONCLUSION: Asymptomatic multivisceral dermatomyositis may mimic metastatic spread of the initially underlying malignancy and may misdirect therapeutic strategies towards inadequate antineoplastic treatment.
机译：目的：报告罕见的复发性原发性副肿瘤性皮肌炎的发作，该发作与最初引发恶性肿瘤完全脱节，表现为无声的纯内脏多发性加重。案例：一名70岁妇女在成功治疗输卵管癌并完全消解伴发副肿瘤性皮肌炎后一年，出现了单纯的多脏器皮肌炎多发性皮肌炎发作，无特征性肌皮症状。反复发生的皮肌炎的罕见表现涉及肺，脾和肝，肾上腺和腹部淋巴结，模仿了高度扩散的输卵管癌复发。参加跨学科肿瘤委员会的医师被误导了选择还原性化疗。仅从多个活检组织获得的组织学诊断才发现该疾病的炎症性质，并使患者无需进行化学疗法。结论：无症状的多脏器皮肌炎可能会模仿最初潜在的恶性肿瘤的转移性扩散，并可能将治疗策略误导为抗肿瘤治疗不足。

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