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首页> 外文期刊>European journal of gynaecological oncology >Successful response to docetaxel treatment in recurrent ovarian granulosa cell tumor: A case report
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Successful response to docetaxel treatment in recurrent ovarian granulosa cell tumor: A case report

机译：多西他赛治疗复发性卵巢颗粒细胞瘤的成功反应：病例报告

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Background: Ovarian granulosa cell tumor (GCT) is primarily treated surgically. Treatment for advanced or recurrent disease includes primary or adjuvant chemotherapy. Data about the efficacy of treatment with paclitaxel are limited, without data about the role of docetaxel in treating recurrent GCT. Case: A 68-year-old patient with Stage IA ovarian GCT diagnosed ten years earlier, presented with a third episode of recurrent disease. Following the first event of recurrent disease, she underwent a second laparotomy followed by BEP chemotherapy. Because of new liver masses, she was treated with paclitaxel, with complete response. Following diagnosis of new liver lesions, third-line chemotherapy with docetaxel was initiated, resulting in stable disease and a PFI of 24 months. Conclusion: Docetaxel might be a good alternative for treating recurrent GCT.
机译：背景：卵巢颗粒细胞瘤（GCT）主要通过手术治疗。晚期或复发性疾病的治疗包括原发或辅助化疗。关于紫杉醇治疗功效的数据有限，而没有关于紫杉醇在治疗复发性GCT中的作用的数据。病例：一名在十年前被诊断为IA期卵巢GCT的68岁患者出现了第三次复发性疾病。在第一次复发性疾病之后，她进行了第二次剖腹手术，随后进行了BEP化疗。由于新的肝脏肿块，她接受了紫杉醇治疗，反应完全。在诊断出新的肝脏病变后，开始用多西他赛进行三线化疗，导致疾病稳定，PFI为24个月。结论：多西他赛可能是治疗复发性GCT的良好选择。

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