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首页> 外文期刊>European journal of gynaecological oncology >Prevalence of endometriosis in epithelial ovarian cancer. Analysis of the associated clinical features and study on molecular mechanisms involved in the possible causality
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Prevalence of endometriosis in epithelial ovarian cancer. Analysis of the associated clinical features and study on molecular mechanisms involved in the possible causality

机译：子宫内膜异位症在上皮性卵巢癌中的患病率。相关临床特征分析和可能因果关系的分子机制研究

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摘要

Purpose of investigation: To determine the prevalence of endometriosis in patients with epithelial ovarian cancer and explore the differences between women with endometrioid and clear-cell histologic subtypes with and without associated endometriosis. Materials and Methods: The medical charts of 496 patients with epithelial ovarian cancer at the Hospital Virgin de la Arrixaca (Murcia, Spain) between 1971 and 2010 were reviewed. Results: Endometriosis was present in 27 (5.4%) of the 496 cases (p < 0001), and was associated with the endometrioid histotype in 13/45 cases (29%) and with the clear cell histotype in 7/22 (32%). The prevalence of an association with endometriosis according to histologic type was 28.8% (13/45) for endometrioid carcinoma and 31.8% (7/22) for clear-cell carcinoma. Conclusion: Both endometrioid and clear-cell ovarians tumours are associated with pelvic endometriosis. Patients with endometiosis associated ovarian cancer differ from non-endometiosis associated ovarian cancer in their clinical characteristics.
机译：研究目的：确定上皮性卵巢癌患者的子宫内膜异位症患病率，探讨子宫内膜异位和透明细胞组织学亚型（有或没有相关子宫内膜异位）的女性之间的差异。资料与方法：回顾了1971年至2010年间在维珍德拉拉阿里萨卡医院（西班牙穆尔西亚）的496例上皮性卵巢癌患者的病历。结果：496例中有27例（5.4％）存在子宫内膜异位（p <0001），13/45例中有子宫内膜样组织学类型（29％），7/22例中有透明细胞组织型（32％）。 ）。根据组织学类型，与子宫内膜异位症相关的患病率对于子宫内膜样癌为28.8％（13/45），对于透明细胞癌为31.8％（7/22）。结论：子宫内膜样和透明细胞卵巢肿瘤均与盆腔子宫内膜异位症相关。子宫内膜异位相关性卵巢癌患者的临床特征与非子宫内膜异位相关性卵巢癌不同。

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