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首页> 外文期刊>European Journal of Radiology >Fecal-tagging CT colonography with structure-analysis electronic cleansing for detection of colorectal flat lesions
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Fecal-tagging CT colonography with structure-analysis electronic cleansing for detection of colorectal flat lesions

机译：带结构分析电子清洗的粪便标记CT结肠造影术，用于检测结直肠扁平病变

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Purpose: To evaluate the feasibility and sensitivity of the 3D-reading of fecal-tagging CT colonography (CTC) with a novel structure-analysis electronic cleansing (SAEC) in detecting colorectal flat lesions in comparison with a cleansed 3D reading with Viatronix V3D Colon system (V3D) and primary uncleansed 2D reading (2D). Materials and methods: Forty CTC cases with flat lesions were retrospectively observed. The Subjects from a multicenter clinical trial underwent cathartic bowel preparation with orally administrated barium-based fecal-tagging. Sixty-nine flat lesions were confirmed using colonoscopy and histopathology as a reference standard. The results from SAEC reading were compared with those of prospective V3D and 2D readings. Results: Overall detection sensitivity with SAEC was 52% (36/69), which was statistically higher than that of 32% (22/69) and 29% (20/69) with V3D and 2D readings, respectively (p < 0.05). The sensitivities in detecting not-on-fold flat lesions were 63% (24/38), 45% (17/38), and 42% (16/38) with SAEC, V3D, and 2D readings, respectively; whereas those of on-fold flat lesions were 39% (12/31), 16% (5/31), and 13% (4/31), respectively. None of the eight flat lesions (2-9 mm) at cecum was detected by any of the three reading methods. Excluding the flat lesions at cecum, the sensitivity with SAEC for detecting flat lesion ≥4 mm increased to 84% (31/37). Conclusions: The fecal-tagging CTC with structure-analysis electronic cleansing could yield a high sensitivity for detecting flat lesions ≥4 mm. The not-on-fold flat lesions were detected with higher sensitivity than on-fold flat lesions.
机译：目的：与采用Viatronix V3D结肠系统清洗后的3D读数相比，使用新型结构分析电子清洗（SAEC）评价粪便标签CT结肠造影（CTC）的3D读数在检测结直肠扁平病变中的可行性和敏感性（V3D）和主要未清洗2D读数（2D）。材料和方法：回顾性观察40例CTC扁平病变病例。来自多中心临床试验的受试者接受了口服钡剂粪便标记的肠通便准备。使用结肠镜检查和组织病理学作为参考标准确认了69个扁平病变。将SAEC读数的结果与预期的V3D和2D读数进行了比较。结果：SAEC的整体检测灵敏度为52％（36/69），在统计学上高于V3D和2D读数分别为32％（22/69）和29％（20/69）（p <0.05） 。用SAEC，V3D和2D读数检测不折叠的扁平病变的敏感性分别为63％（24/38），45％（17/38）和42％（16/38）。折叠型扁平病变分别为39％（12/31），16％（5/31）和13％（4/31）。通过三种读取方法中的任何一种均未检测到盲肠处的八个扁平病变（2-9毫米）。除盲肠处的扁平病变外，SAEC检测≥4mm扁平病变的敏感性提高到84％（31/37）。结论：带结构分析电子清洗的粪便标记四氯化碳可对≥4mm的扁平病变进行检测，具有较高的灵敏度。检测到的非折叠扁平病灶比折叠扁平病灶具有更高的灵敏度。

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