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首页> 外文期刊>European heart journal cardiovascular Imaging >Evaluation of myocardial mechanics with three-dimensional speckle tracking echocardiography in heart transplant recipients: comparison with two-dimensional speckle tracking and relationship with clinical variables
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Evaluation of myocardial mechanics with three-dimensional speckle tracking echocardiography in heart transplant recipients: comparison with two-dimensional speckle tracking and relationship with clinical variables

机译:三维斑点跟踪超声心动图对心脏移植受者心肌力学的评估:与二维斑点跟踪的比较以及与临床变量的关系

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摘要

Two-dimensional speckle-tracking echocardiography (2D-STE) is limited by its inability to track tissue motion in three dimensions. This is particularly relevant in heart transplant recipients, in whom marked translational motion of the transplanted heart is present. We aimed to compare 3-dimensional (3D)- and 2D-STE-derived strain parameters, and to identify clinical features associated with myocardial mechanics in transplant recipients.In 36 heart transplant recipients, global and regional left-ventricular (LV) longitudinal and circumferential strain (LSt and CSt), and radial displacement (RDisp) were obtained by 3D- and 2D-STE, and their results were compared. 3D-STE deformation from a subset of transplant recipients with preserved ejection fraction was compared with a control group of 25 subjects matched by gender, age, history of hypertension, and ejection fraction. Associations between global LSt and CSt and clinical, echocardiographic, and haemodynamic parameters in transplant recipients were investigated. 3D-STE yielded lower magnitude of global LSt compared with 2D-STE (-13 + 3 vs. -16 + 3%, P < 0.001). The inferolateral wall was a source of variation between 3D- and 2D-STE both for LSt and CSt. Inferolateral wall 3D-STE-derived RDisp was greater than that observed in control subjects (7.4 ±1.2 vs. 6.5 + 1.7 mm, P = 0.03), while anteroseptal RDisp was lower than controls (4.2 + 1.0 vs. 7.3 + 1.6 mm, P< 0.001). Multiple regression analysis demonstrated that 3D-STE-derived LSt was independently associated with NYHA class (P< 0.001), while 2D- STE-derived LSt was not.Examination of LV mechanics by 3D- and 2D-STE deformation parameters in heart transplant recipients yields significantly discordant results. 3D-STE-derived LSt is-independently associated with NYHA class, suggesting a clinically important relationship between functional status and myocardial mechanics.
机译:二维斑点跟踪超声心动图(2D-STE)受其无法跟踪三维运动的限制。这在心脏移植受者中特别重要,在接受移植者中,存在着明显的移植心脏的平移运动。我们旨在比较3维(3D)和2D-STE衍生的应变参数,并确定移植受者中与心肌力学相关的临床特征。在36位心脏移植受者中,全球和区域左心室(LV)的纵向和纵向通过3D-STE和2D-STE获得了圆周应变(LSt和CSt)和径向位移(RDisp),并对其结果进行了比较。将保留射血分数的一部分移植受者的3D-STE变形与对照组的25名受试者进行比较,这些受试者的性别,年龄,高血压病史和射血分数匹配。研究了整体LSt和CSt与移植受体的临床,超声心动图和血流动力学参数之间的关联。与2D-STE相比,3D-STE产生的整体LSt幅度较低(-13 + 3与-16 + 3%,P <0.001)。 LSt和CSt的下侧壁是3D和2D-STE之间差异的来源。下侧壁3D-STE衍生的RDisp高于对照组(7.4±1.2 vs. 6.5 + 1.7 mm,P = 0.03),而前中隔RDisp低于对照组(4.2 + 1.0 vs. 7.3 + 1.6 mm, P <0.001)。多元回归分析表明3D-STE衍生的LSt与NYHA类别独立相关(P <0.001),而2D-STE衍生的LSt则不相关。产生明显不一致的结果。 3D-STE衍生的LSt与NYHA类无关,表明功能状态与心肌力学之间存在重要的临床关系。

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