Coronary computed tomography: Current role and future perspectives for cardiovascular risk stratification

Perrone-FilardiP.; MusellaF.; SavareseG.; CecereM.; MarcianoC.; ScalaO.; RengoG.; DellegrottaglieS.; CuocoloA.; LeoscoD.

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Coronary computed tomography: Current role and future perspectives for cardiovascular risk stratification

机译：冠状动脉计算机断层扫描：心血管风险分层的当前作用和未来前景

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Coronary artery disease (CAD) is the major cause of morbidity and mortality worldwide. More than 50% of CAD deaths occur in previously asymptomatic individuals at intermediate cardiovascular risk, highlighting the need of more accurate individual risk assessment to decrease cardiovascular events. Cardiac computed tomography (CCT) has emerged as a valuable technique for risk stratification in asymptomatic subjects and in symptomatic patients without known CAD. The absence of coronary artery calcium (CAC) identifies asymptomatic subjects at very low cardiac risk and is reasonable in intermediate risk individuals, in whom CAC measurement reclassifies a substantial number of subjects to different risk categories. In symptomatic patients with suspected CAD, detection of non-obstructive or obstructive CAD by CCT angiography is associated with increased all-cause mortality, and provides incremental risk stratification to CAC. Further studies are needed to assess the impact of CCT on clinical outcomes and its cost-effectiveness in different clinical settings. Published on behalf of the European Society of Cardiology. All rights reserved.

机译：冠状动脉疾病（CAD）是全世界发病率和死亡率的主要原因。超过50％的CAD死亡发生在心血管疾病处于中等风险的先前无症状的个体中，这突出表明需要进行更准确的个体风险评估以减少心血管事件。心脏计算机断层扫描（CCT）已成为无症状受试者和没有已知CAD的有症状患者风险分层的一种有价值的技术。冠状动脉钙缺乏症（CAC）的存在可将无心脏病的受试者确定为极低的心脏病风险，这在中危人群中是合理的，在这些人群中，CAC测量将大量受试者重新分类为不同的风险类别。在有可疑CAD的症状患者中，通过CCT血管造影检测非阻塞性或阻塞性CAD与全因死亡率增加相关，并为CAC提供了增加的危险分层。需要进一步的研究来评估CCT在不同临床环境中对临床结果的影响及其成本效益。代表欧洲心脏病学会出版。版权所有。

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《European heart journal cardiovascular Imaging》 |2012年第6期|共6页
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Perrone-FilardiP.; MusellaF.; SavareseG.; CecereM.; MarcianoC.; ScalaO.; RengoG.; DellegrottaglieS.; CuocoloA.; LeoscoD.;
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正文语种 eng
中图分类内科学;
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Cardiovascular imaging; Cardiovascular risk; Coronary artery disease; Coronary calcium score; Coronary CT angiography;

机译：心血管成像;心血管风险;冠状动脉疾病;冠状动脉钙化评分;冠状动脉CT血管造影;

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1. Coronary computed tomography: Current role and future perspectives for cardiovascular risk stratification [J] . Perrone-FilardiP., MusellaF., SavareseG., European heart journal cardiovascular Imaging . 2012,第6期

机译：冠状动脉计算机断层扫描：心血管风险分层的当前作用和未来前景
2. ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force (ACCF/AHA Writing Committee to Update the 2000 Expert Consensus Document on Electron Beam Computed Tomography). Developed in Collaboration With the Society of Atherosclerosis Imaging and Prevention and the Society of Cardiovascular Computed Tomography [J] . Greenland P, Bonow RO, Brundage BH, Circulation: An Official Journal of the American Heart Association . 2007,第3期

机译：ACCF / AHA 2007年临床专家共识文件，关于通过计算机断层扫描在全球心血管风险评估和胸痛患者评估中对冠状动脉钙进行评分：美国心脏病学会基金会临床专家共识工作组（ACCF / AHA撰写委员会的报告）更新有关电子束CT的2000年专家共识文件）。与动脉粥样硬化影像学和预防学会以及心血管计算机断层摄影学会合作开发
3. Risk stratification by assessment of coronary artery disease using coronary computed tomography angiography in diabetes and non-diabetes patients: a study from the Western Denmark Cardiac Computed Tomography Registry [J] . Olesen Kevin K. W., Riis Anders H., Nielsen Lene H., European heart journal cardiovascular Imaging . 2019,第11期

机译：糖尿病患者冠状动脉造影评估冠状动脉疾病的风险分层患者：西丹麦心脏计算机断层扫描中的研究
4. Past, present, and future clinical trials ofcardiovascular risk reduction-thehypertension perspective [C] . International Symposium on Atherosclerosis . 2004

机译：过去，现在和未来的心血管风险降低临床试验 - 高血压视角
5. Clarifying the Optimal Management Strategy for Patients with Possible Acute Coronary Syndrome with Intermediate Stenosis and High-Risk Plaque Morphology on Coronary Computed Tomographic Angiography [D] . Dwyer, Stephanie M. 2019

机译：明确可能的急性冠脉综合征合并中度狭窄和高风险斑块形态的冠状动脉计算机断层扫描血管造影的最佳管理策略
6. Role of Computed Tomography for Diagnosis and Risk Stratification of Patients with Suspected or Known Coronary Artery Disease [O] . Dan K. Kalra, Ran Heo, Valentina Valenti, -1

机译：计算机体层摄影术在疑似或已知冠状动脉疾病患者诊断和风险分层中的作用
7. MODERATED EPOSTERS1385Longitudinal strain assessment in dilated cardiomyopathy patients using a novel accelerated DENSE sequence1407Simultaneous T1 and T2 cardiac quantification with CABIRIA: initial clinical experience1423Head-to-head comparison of acceleration algorithms in 4-dimensional flow CMR1502Left ventricular function and size evaluated by hybrid cardiac positron emission tomography-magnetic resonance: Intraindividual comparison of left ventricular ejection fraction and ventricular volumes derived by two modalities1510Left Atrium assessed by Cardiovascular Magnetic Resonance at 1.5 and 3 Tesla – age and gender effects1514Comparison of Free Breathing Cardiac MRI Radial technique to the Standard Multi breath-hold cine SSFP CMR technique for the assessment of LV Volumes and Function1536Self-navigated free-breathing isotropic 3D whole heart phase sensitive inversion recovery magnetic resonance without navigator for detection of myocardial infarction1547Assessment of Right Ventricular Strain Using Myocardial Deformation Recovery Semi Automated Technique: Initial Experience and Normal Values1586Tissue tracking myocardial deformation analysis and prediction of left ventricular remodeling in acute myocardial infarction1589Investigating strategies for optimal 31P MRS clinical cardiac at 3T: Initial Results1620Quantitative Criteria for the Diagnosis of the Congenital Absence of Pericardium by Cardiac Magnetic Resonance1632Widespread tissue injury during acute myocardial infarction: evidence from advanced CMR relaxometry1322Computed tomography coronary angiography verSus sTRess cArdiac magneTic rEsonance for the manaGement of sYmptomatic revascularized patients: a cost effectiveness study (STRATEGY study)1339Comparison of low- versus high-dose of gadobutrol for late gadolinium enhancement imaging at 1.5 Tesla: a clinical feasibility study1347Multi-parametric Cardiac Magnetic Resonance for Prediction of Cardiac Complications in Thalassemia Intermedia: a Prospective Multicenter Study1461Prognostic value of Cardiovascular Magnetic Resonance derived indexes of myocardial fibrosis in heart transplant recipients1523The role of CMR in the acute phase of hospitalization: changing paradigms1542Preoperative CMR-based score predict ventricular response after surgical left ventricular reconstruction in ischemic heart failure patients1555Excellent response rate to cardiac resynchronization therapy guided with magnetic resonance imaging1626The ECG as a predictor of arrhythmogenic substrate on Cardiac Magnetic Resonance Imaging in patients undergoing ablation for premature ventricular contractions1649Comparison of T1-mapping at 3.0T CMR and angiographic APPROACH score for area at risk assessment in ST-segment elevation myocardial infarction1340Pathological correlates of left bundle branch disease in patients with non-ischemic cardiomyopathy: a cardiovascular magnetic resonance study1342Myocardial remodelling and fibrosis in nonischaemic dilated cardiomyopathy: insights from cardiovascular magnetic resonance1411The association between fibrosis and contractile dysfunction in hypertrophic cardiomyopathy assessed by cardiovascular magnetic resonance1622Persistent myocardial inflammation due to intramyocardial haemorrhage in reperfused STEMI as a precursor to adverse LV remodelling - insights from multi-parametric mapping1566Semiquantitative analysis of low and high b value DWI for detecting myocardial edema in acute myocarditis1567Value of Cardiac MRI In Detecting Coronary Artery Disease In Newly Diagnosed Systolic Dysfunction1570Usefulness of cardiac magnetic resonance in tuberous sclerosis complex1578Papillary muscles offer further insight into hypertrophied hearts: a cardiovascular magnetic resonance study1627Diagnostic and clinical implications of CMR timing (early versus late) in patients with troponin positive acute coronary syndromes and unobstructed coronary arteries: Table 1. [O] . Upasana Tayal, Alexandros Kallifatidis, P. Garg, 2016

机译：在使用新的扩张型心肌病的患者缓和EPOSTERS1385Longitudinal应变评估加速DENSE sequence1407Simultaneous T1和T2与CABIRIA心脏定量：在4维流动的加速算法初始临床experience1423Head对头比较CMR1502Left心室功能和尺寸由混合心脏正电子发射断层摄影术评价 - 磁性共振：由两个modalities1510Left庭派生左室射血分数和心室体积的个体间的比较，在1.5和3特斯拉评估心血管磁共振 - 免费的年龄和性别effects1514Comparison呼吸心脏MRI径向技术标准的多屏气电影SSFP CMR技术的LV卷和Function1536Self-导航自由呼吸各向同性3D整个心脏相位敏感反转恢复磁共振导航仪没有检测右Ventricu心肌infarction1547Assessment的评估拉尔菌株使用心肌变形恢复半自动技术：初步经验和正常Values1586Tissue跟踪心肌变形分析和预测左室重构急性心肌infarction1589Investigating策略优化31P MRS临床心脏在3T：初始Results1620Quantitative标准的先天缺失的诊断心包心脏磁Resonance1632Widespread组织损伤急性心肌梗死时：证据先进CMR relaxometry1322Computed CT冠状动脉成像与压力心脏磁共振对症的管理吻合血管患者：成本效益研究（战略研究）1339Comparison低与高剂量钆布醇在1.5特斯拉晚钆增强成像的临床可行性，在中间型地贫心脏并发症的预测study1347Multi参数心脏核磁共振的前瞻性德穆尔心血管磁共振的ticenter Study1461Prognostic价值衍生心肌纤维化指标在住院的急性期CMR的心脏移植recipients1523The作用：改变基于CMR-paradigms1542Preoperative比分预测缺血性心脏衰竭patients1555Excellent响应速度外科左心室重建心脏再同步化后心室反应治疗与磁共振imaging1626The ECG导引作为心脏磁共振成像致心律失常性基板的在ST段抬高心肌infarction1340Pathological在风险评估经历在3.0T CMR T1映射的室性早搏contractions1649Comparison和血管造影APPROACH分数区域消融患者的预测左束支传导疾病的患者与非缺血性心肌病相关因素：心血管磁共振study1342Myocardial重塑和纤维化nonischaemic扩张型心肌病：在从在由心血管磁性resonance1622Persistent心肌炎症评估肥厚型心肌病的纤维化和收缩功能障碍之间心血管磁性resonance1411The协会由于心肌内出血景点在再灌注STEMI为先导，以不利的LV重塑 - 从低的多参数mapping1566Semiquantitative分析和高的b值DWI的见解为在心脏MRI检测冠状动脉疾病急性myocarditis1567Value在结节性硬化症complex1578Papillary肌肉初诊收缩期Dysfunction1570Usefulness心脏磁共振检测心肌水肿提供进一步的深入了解肥大心脏：心血管磁共振study1627Diagnostic和CMR定时的临床意义（早期与晚）患者肌钙蛋白阳性的急性冠脉综合征和通畅的冠状动脉：表1。

Coronary computed tomography: Current role and future perspectives for cardiovascular risk stratification

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