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首页> 外文期刊>European journal of cardio-thoracic surgery: Official journal of the European Association for Cardio-thoracic Surgery >Sacrificing the pulmonary arterial branch to the spared lobe is a risk factor of bronchopleural fistula in sleeve lobectomy after chemoradiotherapy
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Sacrificing the pulmonary arterial branch to the spared lobe is a risk factor of bronchopleural fistula in sleeve lobectomy after chemoradiotherapy

机译：放化疗后，牺牲肺动脉分支至剩余肺叶是支气管胸膜切除术中支气管胸膜瘘的危险因素

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Objectives: A sleeve lobectomy is a widely accepted procedure for enabling the pulmonary parenchyma to be spared. Induction chemoradiotherapy (CRT) followed by surgery is one treatment option for locally advanced non-small cell lung cancer (NSCLC), but CRT is considered to have a negative effect on subsequent surgery, especially for anastomotic healing. In this study, we describe our experience performing sleeve lobectomies and the associated anastomotic complications after induction CRT. Methods: The medical records of NSCLC patients who underwent surgery after receiving CRT were reviewed. The relationships between anastomotic complications and clinicopathological factors were examined. Results: Between December 1998 and October 2011, a total of 104 patients received CRT followed by surgery. Among them, 14 NSCLC patients underwent a bronchial sleeve resection: nine patients underwent a right upper lobe resection, two patients underwent a left lingular division and lower lobe resection and one patient each underwent a right lower lobe, a right upper and middle lobe and a right middle and lower lobe resection. A bronchopleural fistula at the anastomosis occurred in two patients. A pulmonary arterial (PA) branch to the spared lobe had been sacrificed in both of these patients because of tumour involvement. In contrast, the PA branches to the spared lobes were preserved in 11 of the 12 patients who did not exhibit anastomotic complications (P = 0.033). Conclusions: Our experience strongly suggests that the sacrifice of the PA branch to the spared lobe is a possible risk factor for anastomotic complications for a sleeve lobectomy after induction CRT. ? The Author 2012. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
机译：目的：袖状肺叶切除术是使肺实质得以幸免的广泛接受的程序。诱导放化疗（CRT）然后进行手术是局部晚期非小细胞肺癌（NSCLC）的一种治疗选择，但是CRT被认为对后续手术具有负面影响，尤其是对于吻合口愈合。在这项研究中，我们描述了我们在进行CRT后进行袖状肺叶切除术和相关吻合并发症的经验。方法：回顾了接受CRT手术的NSCLC患者的病历。检查了吻合口并发症与临床病理因素之间的关系。结果：在1998年12月至2011年10月之间，共有104例患者接受了CRT手术。其中14例NSCLC患者接受了支气管套管切除术：9例接受了右上叶切除术，2例接受了左舌裂和下叶切除术，1例分别接受了右下叶，右上中叶和右上叶切除术。右中下叶切除。两名患者发生吻合时的支气管胸膜瘘。由于肿瘤受累，在这两名患者中均牺牲了备用肺叶的肺动脉（PA）分支。相反，在没有显示吻合口并发症的12例患者中，有11例保留了保留的肺叶的PA分支（P = 0.033）。结论：我们的经验强烈表明，在诱导CRT后，袖状叶切除术中吻合口并发症的可能危险因素可能是牺牲了PA分支至残叶。 ？作者2012。由牛津大学出版社代表欧洲心胸外科协会出版。版权所有。

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