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Stress and allergic diseases.

机译:压力和过敏性疾病。

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摘要

Allergy describes a constellation of clinical diseases that affect up to 30% of the world's population. It is characterized by production of allergen-specific IgE, which binds to mast cells and initiates a cascade of molecular and cellular events that affect the respiratory tract (rhinitis and asthma), skin (dermatitis, urticaria), and multiple systems (anaphylaxis) in response to a variety of allergens including pollens, mold spores, animal danders, insect stings, foods, and drugs. The underlying pathophysiology involves immunoregulatory dysfunctions similar to those noted in highly stressed populations. The relationships in terms of potential for intervention are discussed.
机译:过敏症描述了一系列影响全世界30%人口的临床疾病。它的特征是产生过敏原特异的IgE,该IgE与肥大细胞结合并引发一系列影响呼吸道(鼻炎和哮喘),皮肤(皮炎,荨麻疹)和多种系统(过敏反应)的分子和细胞事件。对多种过敏原的反应,包括花粉,霉菌孢子,动物皮屑,昆虫ing,食物和药物。潜在的病理生理学涉及免疫调节功能障碍,类似于在高度紧张的人群中注意到的那些。讨论了干预潜力方面的关系。

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