首页> 外文期刊>Immunology: An Official Journal of the British Society for Immunology >Special regulatory T-cell review: Regulatory T cells and the intestinal tract--patrolling the frontier.
【24h】

Special regulatory T-cell review: Regulatory T cells and the intestinal tract--patrolling the frontier.

机译:特殊的调节性T细胞综述:调节性T细胞和肠道-在前沿巡逻。

获取原文
获取原文并翻译 | 示例
           

摘要

Tolerance to self and harmless antigens is one of the central features of the immune system, and it is obtained through a combination of multiple mechanisms. Discriminating between pathogens and non-pathogenic antigens is especially important in the intestine, which constitutes the main contact surface between the body and the outside environment. Recently, the role of Foxp3+ regulatory T cells (Treg) in the establishment and maintenance of tolerance has been the focus of numerous studies. In this review, we briefly discuss the historical background leading to the identification of Foxp3+ Treg and give an overview of their role in controlling systemic and mucosal immune responses.
机译:对自身和无害抗原的耐受性是免疫系统的主要特征之一,它是通过多种机制的组合获得的。在肠道中,区分病原体和非致病性抗原尤为重要,因为肠道是人体与外界环境之间的主要接触面。最近,Foxp3 +调节性T细胞(Treg)在建立和维持耐受性中的作用已成为众多研究的重点。在这篇综述中,我们简要讨论了导致Foxp3 + Treg鉴定的历史背景,并概述了它们在控制全身和粘膜免疫反应中的作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号