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首页> 外文期刊>European surgical research >Total parenteral nutrition is a major risk factor for central venous catheter-related bloodstream infection in colorectal cancer patients receiving postoperative chemotherapy.
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Total parenteral nutrition is a major risk factor for central venous catheter-related bloodstream infection in colorectal cancer patients receiving postoperative chemotherapy.

机译:全肠外营养是接受术后化疗的结直肠癌患者中心静脉导管相关血流感染的主要危险因素。

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摘要

PURPOSE: To clarify the risk factors for central venous catheter-related bloodstream infection (CVCR-BSI) in patients receiving chemotherapy after surgery for colorectal cancer (CRC). METHODS: CVCR-BSI was evaluated retrospectively from a database of patients who had received postoperative chemotherapy using central venous catheters (CVC). RESULTS: One hundred and nine patients received 542 CVC for a total of 5,558 catheter-days. There were no significant differences in background between the patients who had CVCR-BSI and those who did not, except for the administration of total parenteral nutrition (TPN) (p < 0.0001). Moreover, univariate analyses (using factors including type of catheter, sex, age, troubles with insertion, kinds of disinfectant, kinds of catheter, length of inserted catheter, term of catheter insertion and administration of TPN) revealed that the administration of TPN (odds ratio, 12.74; 95% CI, 2.489-62.26; p = 0.0023) was the only risk factor for CVCR-BSI. CONCLUSIONS: TPN is a major risk factor for CVCR-BSI in CRC patients receiving postoperative chemotherapy.
机译:目的:为明确结直肠癌(CRC)术后接受化疗的患者发生中心静脉导管相关血流感染(CVCR-BSI)的危险因素。方法:从数据库中回顾性评估了CVCR-BSI,这些患者使用中央静脉导管(CVC)接受了术后化疗。结果:109例患者接受了542例CVC,共计5558个导管日。接受CVCR-BSI的患者与未接受CVCR-BSI的患者之间,本底无显着差异,除了给予全肠外营养(TPN)外(p <0.0001)。此外,单因素分析(使用因素包括导管的类型,性别,年龄,插入的麻烦,消毒剂的种类,导管的种类,插入的导管的长度,导管的插入期限和TPN的使用)显示TPN的使用(奇数)比例为12.74; 95%CI为2.489-62.26; p = 0.0023)是CVCR-BSI的唯一危险因素。结论:TPN是接受术后化疗的CRC患者CVCR-BSI的主要危险因素。

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