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首页> 外文期刊>Bulletin of the NYU hospital for joint diseases >Limitations of a quantitative swollen and tender joint count to assess and monitor patients with rheumatoid arthritis
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Limitations of a quantitative swollen and tender joint count to assess and monitor patients with rheumatoid arthritis

机译:用于评估和监测类风湿关节炎的定量肿胀和压痛关节计数的局限性

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摘要

A quantitative count of swollen and tender joints is a primary measure to assess patients with rheumatoid arthritis (RA), and is weighted of higher value than the other 5 Core Data Set measures in all indices in which it is included. However, a number of limitations of the swollen and tender joint count have been described in the rheumatology literature, including poor reproducibility, with a requirement to be performed by the same observer at each visit; likelihood to improve with placebo treatment as much or more than the other 5 RA Core Data Set measures in clinical trials; similar or lower relative efficiencies than global and patient measures to document differences between active and control treatments in clinical trials; improvement over 5 years in clinical care, while joint damage and functional disability may progress; and lower sensitivity to detect inflammatory activity than ultrasound. Most visits to a rheumatologist do not include a formal quantitative joint count. It may be suggested that a careful qualitative joint count, supplemented by quantitative patient self-report questionnaire scores, may be more than adequate to monitor and document changes in patient status in busy clinical settings.
机译:肿胀和压痛关节的定量计数是评估类风湿关节炎(RA)患者的主要指标,并且在包括该指标的所有指标中,加权值均高于其他5个核心数据集指标。但是,风湿病学文献已经描述了关节肿胀和压痛的许多局限性,包括重现性差,要求每次访视时由同一位观察者进行。与安慰剂治疗相比,在临床试验中与其他5种RA核心数据集测量值相比,改善的可能性更大或更多;与记录临床试验中主动治疗和对照治疗之间差异的总体和患者措施相比,相对或相似或更低的相对效率;在五年内改善临床护理,同时可能出现关节损伤和功能障碍;并且检测炎症活动的敏感性低于超声。风湿病医生的大多数探访不包括正式的定量关节计数。可能有人建议,仔细的定性关节计数,加上定量的患者自我报告问卷得分,可能足以监测和记录繁忙临床环境中患者状态的变化。

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