...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society >The use of antibiotic-impregnated fibrin sealant for the prevention of surgical site infection associated with spinal instrumentation
【24h】

The use of antibiotic-impregnated fibrin sealant for the prevention of surgical site infection associated with spinal instrumentation

机译：抗生素浸渍的纤维蛋白封闭剂在预防与脊柱器械相关的手术部位感染中的应用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose The purpose of this study was to determine if the use of antibiotic-impregnated fibrin sealant (AFS) was effective in preventing surgical site infections (SSI) associated with spinal instrumentation. Methods In a preliminary study, five pieces of vancomycin-impregnated fibrin sealant, five nuts that were not treated with the sealant, and five nuts that were treated with the sealant were subjected to agar diffusion testing. In a clinical study, the rates of deep SSI were compared between 188 patients who underwent procedures involving spinal instrumentation without AFS (group 1) and 196 patients who underwent procedures involving spinal instrumentation with AFS (group 2). Results All five pieces of vancomycin-impregnated fibrin sealant and the five nuts treated with the sealant exhibited antimicrobial efficacy, while the five untreated nuts did not exhibit antimicrobial efficacy in the agar diffusion test. In the clinical study, 11 (5.8 %) of the 188 patients in group 1 acquired a deep SSI, while none (0 %) of the 196 patients in group 2 acquired a deep SSI. Conclusion The present study demonstrated that the application of AFS to spinal instrumentation yielded good clinical outcomes in terms of the prevention of postoperative spinal infections. It is hoped that limiting AFS use to patients requiring spinal instrumentation and those with risk factors for SSI will reduce the overall costs while preventing SSIs.
机译：目的这项研究的目的是确定使用抗生素浸渍的纤维蛋白封闭剂（AFS）是否能有效预防与脊柱器械相关的手术部位感染（SSI）。方法在一项初步研究中，对5片浸渍万古霉素的纤维蛋白密封剂，5颗未经密封剂处理的坚果和5颗未经密封剂处理的坚果进行琼脂扩散测试。在一项临床研究中，比较了188例行无AFS脊柱器械手术的患者（第1组）和196例行有AFS脊柱器械手术的患者（第2组）。结果所有五片含万古霉素的纤维蛋白封闭剂和五种用封闭剂处理的坚果均表现出抗菌功效，而五种未经处理的坚果在琼脂扩散试验中均未表现出抗菌功效。在临床研究中，第1组188例患者中有11（5.8％）获得了深SSI，而第2组196例患者中没有（0％）获得了深SSI。结论本研究表明，AFS在脊柱器械中的应用在预防术后脊柱感染方面取得了良好的临床效果。希望将AFS仅限于需要脊柱器械的患者和具有SSI危险因素的患者使用，可以减少总体成本，同时预防SSI。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号