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首页> 外文期刊>European radiology >Detection of non-palpable breast cancer in asymptomatic women by using unenhanced diffusion-weighted and T2-weighted MR imaging: comparison with mammography and dynamic contrast-enhanced MR imaging.
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Detection of non-palpable breast cancer in asymptomatic women by using unenhanced diffusion-weighted and T2-weighted MR imaging: comparison with mammography and dynamic contrast-enhanced MR imaging.

机译：通过使用未增强的弥散加权和T2加权MR成像检测无症状女性的非触诊性乳腺癌：与乳腺X线摄影和动态对比增强MR成像的比较。

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OBJECTIVE: To compare the detectability of non-palpable breast cancer in asymptomatic women by using mammography (MMG), dynamic contrast-enhanced MR imaging (DCE-MRI) and unenhanced MR imaging with combined diffusion-weighted and T2-weighted images (DWI+T2WI). METHODS: Forty-two lesions in 42 patients with non-palpable breast cancer in asymptomatic women were enrolled. For the reading test, we prepared a control including 13 normal and 8 benign cases. Each imaging set included biplane MMG, DCE-MRI and DWI+T2WI. Five readers were asked to rate the images on a scale of 0 to 100 for the likelihood of the presence of cancer and the BI-RADS category. Confidence level results were used to construct receiver operating characteristic analysis. Sensitivity and specificity were calculated for each technique. RESULTS: DWI+T2WI showed higher observer performances (area under the curve, AUC, 0.73) and sensitivity (50%) for the detection of non-palpable breast cancer than MMG alone (AUC 0.64; sensitivity 40%) but lower than those of DCE-MRI (AUC 0.93; sensitivity 86%). A combination of MMG and DWI+T2WI exhibited higher sensitivity (69%) compared with that of MMG alone (40%). CONCLUSION: DWI+T2WI could be useful in screening breast cancer for patients who cannot receive contrast medium and could be used as a new screening technique for breast cancer.
机译：目的：使用乳腺X线摄影（MMG），动态对比增强MR成像（DCE-MRI）和未增强MR成像，结合弥散加权和T2加权图像（DWI + T2WI）。方法：对42例无症状乳腺癌的42例病灶进行了研究。对于阅读测试，我们准备了包括13例正常病例和8例良性病例的对照。每个成像集包括双翼飞机MMG，DCE-MRI和DWI + T2WI。要求五名读者以0到100的等级对图像进行评分，以评估是否存在癌症和BI-RADS类别。置信水平结果用于构建接收器工作特性分析。计算每种技术的敏感性和特异性。结果：DWI + T2WI表现出较高的观察者表现（曲线下面积，AUC，0.73）和灵敏度（50％），高于单独的MMG（AUC 0.64;灵敏度40％），但低于后者。 DCE-MRI（AUC 0.93;灵敏度86％）。与单独的MMG（40％）相比，MMG和DWI + T2WI的组合具有更高的灵敏度（69％）。结论：DWI + T2WI可用于筛查不能接受造影剂的患者，可作为一种新的乳腺癌筛查技术。

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