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首页> 外文期刊>European radiology >Brain perfusion measured by flow-sensitive alternating inversion recovery (FAIR) and dynamic susceptibility contrast-enhanced magnetic resonance imaging: comparison with nuclear medicine technique.
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Brain perfusion measured by flow-sensitive alternating inversion recovery (FAIR) and dynamic susceptibility contrast-enhanced magnetic resonance imaging: comparison with nuclear medicine technique.

机译：通过血流敏感交替反转恢复（FAIR）和动态磁化率对比增强磁共振成像测量脑灌注：与核医学技术的比较。

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The aim of this study was to compare cerebral perfusion images and regional cerebral blood flow (rCBF) of SPECT study with the images and regional intensity of relative cerebral blood flow (CBF) images acquired by contrast-enhanced perfusion MR imaging (pMRI) and flow-sensitive alternating inversion recovery (FAIR). Twelve patients with various cerebral diseases were underwent I-123-IMP SPECT, pMRI, and FAIR studies to measure rCBF. A total of 12 regions of interest (ROI) were created over cerebrum and cerebellum to acquire the corresponding rCBF from I-123-IMP study and regional average signal intensity from CBF images of pMRI and FAIR studies. Left-to-right (L/R) and cerebral-to-cerebellar (CCR) ratios were created from the rCBF of I-123-IMP and signal intensity of CBF images of pMRI and FAIR. Image quality of FAIR was the poorest among all; however, CBF images of pMRI and FAIR images show comparatively decreased intensity at the corresponding site of decreased perfusion on I-123-IMP images. Both FAIR and pMRI images showed high intensity along the sinuses, choroid plexus, and large vessels in sulci. No significant correlation was found among all imaging modalities. But L/R ratio of I-123-IMP showed significant correlation with those of pMRI and FAIR, but for CCR, significant correlation was observed only between I-123-IMP and FAIR. Perfusion images of both pMRI and FAIR may produce images comparable to SPECT study. But to calculate absolute CBF more easy-to-apply and accurate algorithms are needed to overcome the artifacts from large vessels.
机译：这项研究的目的是将SPECT研究的脑灌注图像和局部脑血流（rCBF）与通过对比增强灌注MR成像（pMRI）和血流获取的相对脑血流（CBF）图像的图像和区域强度进行比较敏感交替反转恢复（FAIR）。对12名患有各种脑部疾病的患者进行了I-123-IMP SPECT，pMRI和FAIR研究，以测量rCBF。在大脑和小脑上共创建了12个感兴趣的区域（ROI），以从I-123-IMP研究获得相应的rCBF，并从pMRI和FAIR研究的CBF图像获得区域平均信号强度。从I-123-IMP的rCBF以及pMRI和FAIR的CBF图像的信号强度创建左右（L / R）和脑小脑（CCR）比。 FAIR的图像质量是最差的;然而，pMRI和FAIR图像的CBF图像在I-123-IMP图像上相应的灌注减少部位显示出相对较低的强度。 FAIR和pMRI图像均显示沿窦，脉络丛和沟内大血管的高强度。在所有成像方式之间均未发现显着相关性。但是，I-123-IMP的L / R比与pMRI和FAIR呈显着相关，但对于CCR，仅在I-123-IMP和FAIR之间观察到显着相关。 pMRI和FAIR的灌注图像可产生与SPECT研究相当的图像。但是，要计算绝对CBF，需要更易于应用和精确的算法来克服大型船只的假象。

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