Circulating CLA+ T lymphocytes as peripheral cell biomarkers in T-cell-mediated skin diseases

FerranM.; RomeuE.R.; RincónC.; SagristàM.; GiménezArnauA.M.; CeladaA.; PujolR.M.; HollóP.; JókaiH.; Santamaria-BabíL.F.

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Circulating CLA+ T lymphocytes as peripheral cell biomarkers in T-cell-mediated skin diseases

机译：循环中的CLA + T淋巴细胞作为T细胞介导的皮肤疾病的外周细胞生物标志物

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T lymphocytes expressing the CLA antigen constitute a subset of effector memory lymphocytes that are functionally involved in T-cell-mediated cutaneous diseases. Skin-seeking lymphocytes recirculate between inflamed skin and blood during cutaneous inflammation. Many studies in different T-cell-mediated inflammatory cutaneous diseases have clearly related their pathologic mechanisms to CLA+ T cells. Based on common features of these cells in different cutaneous disorders mediated by T cells, we propose that circulating CLA+T cells could constitute very useful peripheral cellular biomarkers for T-cell-mediated skin diseases.

机译：表达CLA抗原的T淋巴细胞构成了功能性参与T细胞介导的皮肤疾病的效应记忆淋巴细胞的子集。皮肤炎症过程中，寻求皮肤的淋巴细胞在发炎的皮肤和血液之间循环。在不同的T细胞介导的炎性皮肤疾病中的许多研究已明确将其病理机制与CLA + T细胞相关。基于这些细胞在T细胞介导的不同皮肤疾病中的共同特征，我们建议循环中的CLA + T细胞可以构成T细胞介导的皮肤疾病的非常有用的外周细胞生物标志物。

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来源
《Experimental dermatology》 |2013年第7期|共4页
作者
FerranM.; RomeuE.R.; RincónC.; SagristàM.; GiménezArnauA.M.; CeladaA.; PujolR.M.; HollóP.; JókaiH.; Santamaria-BabíL.F.;
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正文语种 eng
中图分类皮肤病学与性病学;
关键词
Associated antigen; Biomarker; Cutaneous lymphocyte; Skin-homing; T lymphocyte;

机译：相关抗原;生物标志物;白细胞;归巢;T淋巴细胞;

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1. Circulating CLA+ T lymphocytes as peripheral cell biomarkers in T-cell-mediated skin diseases [J] . FerranM., RomeuE.R., RincónC., Experimental dermatology . 2013,第7期

机译：循环中的CLA + T淋巴细胞作为T细胞介导的皮肤疾病的外周细胞生物标志物
2. Hyperbaric Oxygen Therapy Enhanced Circulating Levels of Endothelial Progenitor Cells and Angiogenesis Biomarkers, Blood Flow, in Ischemic Areas in Patients with Peripheral Arterial Occlusive Disease [J] . Pao-Yuan Lin, Pei-Hsun Sung, Sheng-Ying Chung, Journal of Clinical Medicine . 2018,第12期

机译：高压氧疗法增强了外周动脉闭塞性疾病患者缺血区域的内皮祖细胞循环水平和血管生成生物标志物，血流量。
3. Transcriptional Analysis of Blood Lymphocytes and Skin Fibroblasts, Keratinocytes, and Endothelial Cells as a Potential Biomarker for Alzheimer's Disease [J] . Mukhamedyarov Marat A., Rizvanov Albert A., Yakupov Eduard Z., Journal of Alzheimer's disease: JAD . 2016,第4期

机译：血液淋巴细胞和皮肤成纤维细胞，角质形成细胞和内皮细胞的转录分析作为阿尔茨海默氏病的潜在生物标志物
4. Abnormal peripheral blood T lymphocyte cell subsets in a subgroup of patients with chronic obstructive pulmonary disease [C] . Won-Dong Kim, Woo-Sung Kim, Younsuck Koh, . 2002

机译：慢性阻塞性肺疾病患者亚组的外周血T淋巴细胞异常
5. Bioinformatics and biomolecular tools for biomarker discovery in peripheral blood lymphocytes from patients with sporadic amyotrophic lateral sclerosis. [D] . Baciu, Cristina. 2012

机译：在散发性肌萎缩性侧索硬化症患者外周血淋巴细胞中发现生物标志物的生物信息学和生物分子工具。
6. The Prognostic Roles of Pretreatment Circulating Tumor Cells, Circulating Cancer Stem-Like Cells, and Programmed Cell Death-1 Expression on Peripheral Lymphocytes in Patients with Initially Unresectable, Recurrent or Metastatic Head and Neck Cancer: An Exploratory Study of Three Biomarkers in One-time Blood Drawing [O] . Pei-Hung Chang, Min-Hsien Wu, Sen-Yu Liu, 1926

机译：初始不可切除，复发或转移性头颈癌患者中预处理循环肿瘤细胞，循环癌干细胞和程序性细胞死亡1表达对外周淋巴细胞的预后作用：一次性研究三种生物标志物抽血
7. Circulating CLA+T lymphocytes as peripheral cell biomarkers in T-cell-mediated skin diseases [O] . Ferran M, Romeu ER, Rincón C, 2014

机译：循环CLa + T淋巴细胞作为T细胞介导的皮肤病中的外周细胞生物标志物
8. Cells, Biomarkers, and Posttraumatic Stress Disorder: Evidence for Peripheral Involvement in a Central Disease. [R] . J. A. Andrews K. D. Neises 2012

机译：细胞，生物标志物和创伤后应激障碍：外周参与中枢性疾病的证据。

Circulating CLA+ T lymphocytes as peripheral cell biomarkers in T-cell-mediated skin diseases

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