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首页> 外文期刊>Experimental and clinical endocrinology and diabetes: Official journal, German Society of Endocrinology [and] German Diabetes Association >In-hospital mortality in a tertiary referral hospital: causes of death and comparison between patients with and without diabetes.
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In-hospital mortality in a tertiary referral hospital: causes of death and comparison between patients with and without diabetes.

机译:三级转诊医院的院内死亡率:死亡原因以及有无糖尿病患者之间的比较。

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INTRODUCTION: Subjects with type 2 diabetes mellitus (T2DM) have increased morbidity and mortality mainly due to macrovascular complications. In addition, diabetic patients show increased in-hospital admissions in comparison with nondiabetic patients. However, in-hospital mortality data for patients with T2DM are not available in our country. The aim of the present study was to examine mortality rates in diabetic compared to nondiabetic patients admitted to a tertiary hospital during a 10-year period (1998-2007). MATERIAL AND METHODS: We performed a retrospective analysis of mortality rates in patients with and without T2DM hospitalised in a tertiary care hospital during the years 1998-2007. Demographic characteristics, medical history and outcome were collected from the patients' medical records. Patients with type 1 diabetes were excluded from the analysis. RESULTS: A total of 16 125 patients' records were studied (14 005 without diabetes and 2 120 with T2DM). In the total sample, 1 467 (9.1%) deaths were recorded. Mortality rates were higher in the diabetic than in the nondiabetic patients (11.2% versus 8.7%, respectively, p<0.001). Age of death did not differ between diabetic and nondiabetic patients (age+/-SD: 77.1+/-9.5 vs. 77.6+/-16.3 years, p=0.73). Median length of hospital stay was higher in the diabetic than in the nondiabetic patients (p=0.03). Mortality was higher in the diabetic in comparison with the nondiabetic females (59.9% vs. 52.7%, respectively, p=0.04), while no gender difference was found in males. Cerebrovascular disease was the commonest cause of death in both diabetic and nondiabetic patients (41.6% vs. 30.3%, p=0.001), followed by infections (23.1% vs. 21.7%, respectively, p=0.62). Death rates from malignancies were more common in the nondiabetic in comparison with the diabetic patients (18.8% vs. 4.2%, p<0.001). No significant differences were observed between the two study groups regarding mortality caused by cardiovascular events and chronic renal failure. CONCLUSION: The present study showed that diabetic patients and especially females had increased in-hospital mortality compared with nondiabetic patients. Cerebrovascular disease and infections were the more common cause of death in both groups.
机译:简介:2型糖尿病(T2DM)患者的发病率和死亡率增加,主要是由于大血管并发症引起的。此外,与非糖尿病患者相比,糖尿病患者的住院住院人数增加。但是,我国尚无2型糖尿病患者的院内死亡率数据。本研究的目的是检查在十年期间(1998年至2007年),三级医院住院的非糖尿病患者与非糖尿病患者的死亡率。材料与方法:我们对1998-2007年期间在三级医院住院的有无T2DM的患者的死亡率进行了回顾性分析。从患者的病历中收集人口统计学特征,病史和结局。 1型糖尿病患者被排除在分析之外。结果:共研究了16125例患者的病历(无糖尿病的14005例和2型糖尿病的2120例)。在总样本中,记录了1 467(9.1%)人死亡。糖尿病患者的死亡率高于非糖尿病患者(分别为11.2%和8.7%,p <0.001)。糖尿病患者和非糖尿病患者的死亡年龄没有差异(年龄+/- SD:77.1 +/- 9.5与77.6 +/- 16.3岁,p = 0.73)。糖尿病患者的中位住院时间长于非糖尿病患者(p = 0.03)。与非糖尿病女性相比,糖尿病患者的死亡率更高(分别为59.9%和52.7%,p = 0.04),而男性没有发现性别差异。在糖尿病和非糖尿病患者中,脑血管疾病是最常见的死亡原因(分别为41.6%和30.3%,p = 0.001),其次是感染(分别为23.1%和21.7%,p = 0.62)。与糖尿病患者相比,非糖尿病患者的恶性肿瘤死亡率更高(18.8%vs. 4.2%,p <0.001)。在两个研究组之间,在心血管事件和慢性肾功能衰竭引起的死亡率方面没有观察到显着差异。结论:本研究表明,与非糖尿病患者相比,糖尿病患者,尤其是女性的住院死亡率增加。脑血管疾病和感染是两组中较常见的死亡原因。

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