Immune-cell poor Hgf-Cdk4 mouse melanomas benefit from antibody mediated PD-1 blockade after targeted activation of the type I IFN system

Bald T.; Landsberg J.; Lopez D.; Renn M.; Glodde N.; Jansen P.; Gaffal E.; Joensson G.; Hoelzel M.; Tueting T.

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Immune-cell poor Hgf-Cdk4 mouse melanomas benefit from antibody mediated PD-1 blockade after targeted activation of the type I IFN system

机译：I型干扰素系统靶向激活后，免疫细胞不良的Hgf-Cdk4小鼠黑素瘤受益于抗体介导的PD-1阻断

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《Experimental dermatology》 |2015年第3期|共2页
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Bald T.; Landsberg J.; Lopez D.; Renn M.; Glodde N.; Jansen P.; Gaffal E.; Joensson G.; Hoelzel M.; Tueting T.;
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正文语种 eng
中图分类皮肤病学与性病学;
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1. Immune-cell poor Hgf-Cdk4 mouse melanomas benefit from antibody mediated PD-1 blockade after targeted activation of the type I IFN system [J] . Bald T., Landsberg J., Lopez D., Experimental dermatology . 2015,第3期

机译：I型干扰素系统靶向激活后，免疫细胞不良的Hgf-Cdk4小鼠黑素瘤受益于抗体介导的PD-1阻断
2. PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody [J] . They Laetitia, Michaud Henri-Alexandre, Becquart Ondine, Oncoimmunology. . 2017,第10期

机译：肿瘤逃逸时PD-1阻断增强了黑色素瘤靶向单克隆抗体的免疫介导的抗肿瘤作用
3. Poor outcome with anti-programmed death-ligand 1 (PD-L1) antibody due to poor pharmacokinetic properties in PD-1/PD-L1 blockade-sensitive mouse models [J] . Taiki Kurino, Reiko Matsuda, Ayu Terui, Journal for ImmunoTherapy of Cancer . 2020,第1期

机译：由于PD-1 / PD-L1封闭式小鼠模型中的药代动力学特性差，抗程序死亡 - 配体1（PD-L1）抗体差
4. Targeted Disruption of the IMPDH: Type Ⅱ Gene: Effect on Mouse Development and Lymphocyte Activation [C] . Jing Jin Gu, Sander Stegmannl, Beverly S. Mitchell Symposium on Inosine Monophosphate Dehydrogenase: A Major Therapeutic Target null null . 2000

机译：IMPDH的靶向破坏：Ⅱ型基因：对小鼠发育和淋巴细胞活化的影响
5. Targeting melanoma associated antigens with antigen-specific antibodies: An examination of mechanisms and strategies in two antigen systems [D] . Hsu, Jeff Chi-Feng. 2007

机译：用抗原特异性抗体靶向黑色素瘤相关抗原：两种抗原系统的机制和策略研究
6. PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody [O] . Laetitia They, Henri-Alexandre Michaud, Ondine Becquart, 2017

机译：肿瘤逃逸时的PD-1阻断增强了靶向黑色素瘤的单克隆抗体的免疫介导的抗肿瘤作用
7. Immune Cell-Poor Melanomas Benefit from PD-1 Blockade after Targeted Type I IFN Activation [O] . Bald, Tobias, Landsberg, Jennifer, Limmer, Andreas, 2014

机译：靶向I型IFN激活后，PD-1阻断可提高免疫细胞不良黑素瘤的价值

Immune-cell poor Hgf-Cdk4 mouse melanomas benefit from antibody mediated PD-1 blockade after targeted activation of the type I IFN system

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