Relationship between antipsychotic medication, serum prolactin levels and osteoporosis/osteoporotic fractures in patients with schizophrenia: a critical literature review

De Hert Marc; Detraux Johan; Stubbs Brendon

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Relationship between antipsychotic medication, serum prolactin levels and osteoporosis/osteoporotic fractures in patients with schizophrenia: a critical literature review

机译：精神分裂症患者抗精神病药物，血清催乳素水平与骨质疏松/骨质疏松性骨折之间的关系：文献综述

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Introduction: Using an antipsychotic medication can increase prolactin (PRL) levels, causing hyperprolactinemia (HPRL). Although the occurrence of osteoporosis within the population of patients with schizophrenia has been recognized, the precise nature of the association between antipsychotic treatment, PRL, osteoporosis, and the disease itself seems to be elusive.

机译：简介：使用抗精神病药会增加催乳素（PRL）的水平，从而引起高催乳素血症（HPRL）。尽管已经认识到精神分裂症患者人群中骨质疏松症的发生，但抗精神病药物治疗，PRL，骨质疏松症和疾病本身之间的确切关系似乎难以捉摸。

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《Expert opinion on drug safety》 |2016年第6期|共15页
作者
De Hert Marc; Detraux Johan; Stubbs Brendon;
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正文语种 eng
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Hyperprolactinemia; schizophrenia; antipsychotic; prolactin; osteoporosis; fracture;

机译：高泌乳素血症;精神分裂症;抗精神病药;催乳素;骨质疏松症;骨折;

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1. Relationship between antipsychotic medication, serum prolactin levels and osteoporosis/osteoporotic fractures in patients with schizophrenia: a critical literature review [J] . De Hert Marc, Detraux Johan, Stubbs Brendon Expert opinion on drug safety . 2016,第6期

机译：精神分裂症患者抗精神病药物，血清催乳素水平与骨质疏松/骨质疏松性骨折之间的关系：文献综述
2. Second-generation and newly approved antipsychotics, serum prolactin levels and sexual dysfunctions: A critical literature review [J] . DeHertM., DetrauxJ., PeuskensJ. Expert opinion on drug safety . 2014,第5期

机译：第二代和新批准的抗精神病药，血清催乳素水平和性功能障碍：重要文献综述
3. Relationship between prolactin, breast cancer risk, and antipsychotics in patients with schizophrenia: a critical review [J] . De Hert M., Peuskens J., Sabbe T., Acta Psychiatrica Scandinavica . 2016,第1期

机译：精神分裂症患者催乳素，乳腺癌风险和抗精神病药之间的关系：一项重要的审查。
4. Antipsychotic medication influences cardiovascular coupling in patients suffering from acute schizophrenia [C] . Schulz Steffen, Haueisen Jens, Bar Karl-Jurgen, Computing in Cardiology Conference . 2014

机译：抗精神病药会影响急性精神分裂症患者的心血管耦合
5. Exploring Patients' Perception of Osteoporosis Following a Fragility Fracture: Results of a Literature Review and Analysis of a Provincial Database. [D] . Sujic, Rebeka. 2011

机译：探索患者对脆性骨折后骨质疏松症的感知：文献回顾和省级数据库分析的结果。
6. The effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913) [O] . Linda Hanssens, Gilbert LItalien, Jean-Yves Loze, 2008

机译：抗精神病药物对社区治疗的精神分裂症患者性功能和血清催乳素水平的影响：阿立哌唑精神分裂症试验（STAR）研究的结果（NCT00237913）
7. The effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913) [O] . Linda Hanssens, Gilbert LItalien, Jean-Yves Loze, 2008

机译：抗精神病药物对社区治疗的精神分裂症患者性功能和血清催乳素水平的影响：阿立哌唑精神分裂症试验（STAR）研究的结果（NCT00237913）

Relationship between antipsychotic medication, serum prolactin levels and osteoporosis/osteoporotic fractures in patients with schizophrenia: a critical literature review

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