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Imaging of neuroendocrine tumors

机译：神经内分泌肿瘤的影像学

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摘要

The imaging needs in the individual neuroendocrine tumor (NET) patient are very diverse and the choice of method, or combination of techniques, depends on the characteristics of the particular type of NET and its presentation. Areas covered: The various morphological and functional imaging methods and important methodological aspects are described. The imaging requirements for the various NET subtypes are explained and typical NET image findings are described and illustrated. Expert opinion: The choice of the optimum imaging techniques is not only a matter of sensitivity and specificity but must also be considered in the light of the local availability and expertise in the department. Familiarity with contrast-enhancement technique for computed tomography (CT) and magnetic resonance imaging (MRI) is important in the interpretation and understanding of the imaging results. MRI including diffusion weighted imaging (DWI) for oncological imaging has been reported to improve tumor visualization and reader confidence and is expected to similarly be beneficial for NET imaging. Positron emission tomography (PET) using 68Ga-labeled somatostatin analogs is in several aspects superior to somatostatin receptor scintigraphy using Octreoscan?. Molecular imaging problem-solving tools, when PET/CT using 68Ga-labeled somatostatin analogs fails, are PET/CT with 11C-5-HTP and 18F-DOPA.
机译：单个神经内分泌肿瘤（NET）患者的影像需求非常多样化，方法或技术组合的选择取决于NET的特定类型及其显示方式。涵盖的领域：描述了各种形态和功能成像方法以及重要的方法学方面。解释了各种NET子类型的成像要求，并描述和说明了典型的NET图像发现。专家意见：最佳成像技术的选择不仅是灵敏度和特异性的问题，而且还必须考虑该部门的本地可用性和专业知识。熟悉计算机断层扫描（CT）和磁共振成像（MRI）的对比度增强技术对于解释和理解成像结果很重要。据报道，包括用于肿瘤成像的弥散加权成像（DWI）在内的MRI可改善肿瘤的可视性和读者的信心，并有望同样有利于NET成像。使用68Ga标记的生长抑素类似物的正电子发射断层扫描（PET）在几个方面优于使用Octreoscan？的生长抑素受体闪烁显像。当使用68Ga标记的生长抑素类似物的PET / CT失败时，分子成像问题解决工具将是具有11C-5-HTP和18F-DOPA的PET / CT。

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