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首页> 外文期刊>Expert opinion on pharmacotherapy >Medical management of polymyalgia rheumatica.
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Medical management of polymyalgia rheumatica.

机译：风湿性多肌痛的医疗管理。

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IMPORTANCE OF THE FIELD: Polymyalgia rheumatica (PMR) is a relatively frequent condition in individuals older than 50 who originate from Western countries. Corticosteroids constitute the cornerstone therapy in the management of patients with PMR. AREAS COVERED IN THIS REVIEW: This review summarizes the current literature on clinical clues for the diagnosis of PMR, conditions mimicking PMR, relapses in the setting of PMR and the main therapeutic strategies. WHAT THE READER WILL GAIN: With this information, the reader receives an overview on the current available data on clinical diagnosis and treatment options in PMR. TAKE-HOME MESSAGES: An initial dose of prednisone of 10-20 mg/day yields clinical improvement in the majority of patients with PMR. This is generally achieved within 7 days of the onset of this therapy. Conditions different from isolated PMR should be considered in atypical cases or when a good response to 20 mg/day of prednisone is not achieved. Relapses of PMR are not uncommon when the dose of prednisone is equal to or below than 5 mg/day. Methotrexate is the most commonly used corticosteroid sparing agent. Osteoporosis prophylaxis is also recommended.
机译：领域的重要性：风湿性多肌痛（PMR）在来自西方国家的50岁以上的个体中相对常见。皮质类固醇是治疗PMR患者的基石疗法。本综述涵盖的领域：这篇综述总结了有关PMR诊断的临床线索，模拟PMR的病症，PMR的复发和主要治疗策略的最新文献。读者将会获得什么：有了这些信息，读者将获得有关PMR中临床诊断和治疗选择的当前可用数据的概述。随身携带的信息：泼尼松的初始剂量为10-20 mg /天，在大多数PMR患者中可产生临床改善。通常在该疗法开始后7天内即可实现。在非典型情况下或对强的松每天20 mg不能产生良好反应时，应考虑与孤立的PMR不同的条件。当泼尼松的剂量等于或低于5毫克/天时，PMR的复发并不罕见。甲氨蝶呤是最常用的皮质类固醇保护剂。还建议预防骨质疏松症。

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