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Pharmacotherapy of multiple myeloma.

机译:多发性骨髓瘤的药物治疗。

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摘要

Multiple myeloma is a malignant process of the plasma cell. There is no cure for this disease and at present the focus is to manage the disease as a chronic process to achieve a good quality of life. Hopefully, with the advancement in the understanding of the pathophysiology of the disease, target therapy should allow for the control of multiple myeloma, its prevention, and/or the reversal of organ damage; therefore prolonging survival. Proteasome inhibitors and immune modulators are the first of new therapies that target the malignant plasma cell microenvironment. In this review, different aspects of these agents are discussed.
机译:多发性骨髓瘤是浆细胞的恶性过程。目前尚无治愈该疾病的方法,目前的重点是将疾病作为一种长期过程来控制,以实现良好的生活质量。希望随着对疾病病理生理学认识的提高,目标疗法应能控制多发性骨髓瘤,预防和/或逆转器官损伤;因此延长了生存期。蛋白酶体抑制剂和免疫调节剂是针对恶性浆细胞微环境的新疗法中的第一个。在这篇综述中,讨论了这些代理的不同方面。

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