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首页> 外文期刊>Experimental Gerontology >Risk factors, causality, and policy initiatives: the case of aluminum and mental impairment.
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Risk factors, causality, and policy initiatives: the case of aluminum and mental impairment.

机译:风险因素,因果关系和政策措施:铝和精神障碍的情况。

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摘要

The question addressed is when can the evidence concerning a health issue be regarded as adequate to implement policy initiatives. The approach is illustrated by comparing evidence about the effects of cigarette smoking with evidence for the aluminum (Al) hypothesis (that Al contributes to mental impairment and especially to Alzheimer's Disease). The criteria for evaluating the evidence are based on the consistency and strength of the association between a putative risk factor and the relevant outcome variable, the likelihood that the relative risk represents a causal relationship, whether possible mechanisms are available, the number of persons affected, and the costs of modifying the risk factor.
机译:解决的问题是,何时可以将有关健康问题的证据视为足以实施政策措施。通过将有关吸烟影响的证据与铝(Al)假说(Al导致精神障碍,尤其是阿尔茨海默氏病)的证据进行比较,说明了该方法。评估证据的标准基于推定的风险因素与相关结果变量之间关联的一致性和强度,相对风险代表因果关系的可能性,是否有可能的机制,受影响的人数,以及修改风险因素的成本。

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